+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Preparation of steroidal 5 beta 6 beta epoxides and their oxidation by chromium trioxide

, : Preparation of steroidal 5 beta 6 beta epoxides and their oxidation by chromium trioxide. Journal of the Chemical Society Perkin Transactions I (7): 2001-2004

Reaction of 3.alpha.-chloroandrost-5-en-17-one with m-chloroperbenzoic acid affords the 5.beta.,6.beta.-epoxide. This is accomplished by some Baeyer-Villiger oxidation at C-17. The 3.alpha.-chlorine atom can be removed by hydrogenolysis with tributyltin hydride. Although the unsubstituted 5.beta.,5.beta.-epoxide is oxidized by chromium trioxide to the 5.alpha.-hydroxy 6-ketone, the 3.alpha.-chloro 5.beta.,6.beta.-epoxide is unreactive.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006173970

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Soto-Blanco, Jose-Manuel; Perez, Isabel-Ruiz; De-Labry-Lima, Antonio-Olry; Castro-Recio, Jose-Manuel; Girela-Lopez, Eloy; Anton-Basanta, Jose-Joaquin, 2005: Adherence to antiretroviral treatment in prisons. The effectiveness of antiretroviral drugs is closely linked to the degree of adherence. The prison environment has specific characteristics that may affect adherence in HIV-positive patients, so that it may not be possible to extrapolate factors a...

Baluch, Maa, 1981: Transfer of cotton technology to farmers. Pakistan agriculture 3(10): 15-17

Tsumura, Yukari; Goto, Yunosuke; Munakata, Nozomi; Nakamura, Yumiko; Tonogai, Yasuhide; Shibata, Tadashi, 1996: Determination of fenarimol and lenacil in agricultural products by GC. Fenarimol and lenacil in agricultural products were determined using the method previously reported by the authors (Shokuhin Eiseigaku Zasshi 36(5), 613 apprx 621 (1995)). Ten grams of grain or 20 g of vegetable or fruit was homogenized with aceto...

Akiba, J.; Yanagiya, N.; Kakehashi, A.; Hikichi, T.; Kado, M.; Yoshida, A.; Ueno, N., 1996: Copper ion catalyzed vitreous liquefaction in vivo. Investigative Ophthalmology & Visual Science 37(3): S787

Yahata, T., 1973: Induced spawning of abalone (Nordotis discus Reeve) injected with ganglional suspensions. Bulletin Jap Soc Scient Fish, 3911: 1117-1122

Wittmann, Sigrid; Daniels, Stephen; Ittner, Karl Peter; Froehlich, Dieter, 2002: Effects of the Stereoisomers of Thiopentone and Methohexitone on the fMLP Induced Oxidative Response in Human Neutrophils In Vitro. Introduction: The commercially available racemate of methohexitone suppresses the fMLP induced oxidative response in human neutrophils in vitro to a lesser extent than thiopentone (1). For thiopentone single enantiomers are available for in vitro...

Bujons, Jordi; Dikiy, Alexander; Ferrer, Juan, C.; Banci, Lucia; Mauk, A. Grant, 1997: Charge reversal of a critical active-site residue of cytochrome-c peroxidase: Characterization of the Arg48 fwdarw Glu variant. A new variant of cytochrome-c peroxidase in which the positively charged Arg48 present in the distal heme-binding pocket has been replaced with a Glu residue has been prepared and characterized to explore, in part, the possibility that a negative...

Al Darby Ali M.; Al Sheikh Abdullah A., 1995: The combined effect of soil gel-conditioner and irrigation water quality and level on; 1, Soil water retention and availability, water and salt distribution in sandy soil. Arab Gulf Journal of Scientific Research 13(3): 719-748

Novotny, J.; Zinek, K., 1994: Application of epirubicin containing albumin microspheres in the experimental therapy of breast cancer. Neoplasma (Bratislava) 41(4): 201-204

Seibert M., 1973: Light the effects of wave length and intensity on growth and shoot initiation in tobacco callus. In Vitro (Rockville) 8(5): 435