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Preparation of sub viral particles from vaccinia virions irradiated with uv light






Journal of Virological Methods 1(4): 185-196

Preparation of sub viral particles from vaccinia virions irradiated with uv light

Nucleoprotein complexes, containing proteins covalently bound to DNA, were prepared from vaccinia virions irradiated with ultraviolet light. EM showed that these complexes had a spherical morphology with a densely staining central portion, apparently containing proteins cross-linked to DNA, from which loops or fibers of DNA or DNA complexed with protein emerged.

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Accession: 006173975



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