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Primary screening of viral inhibitors in tissue culture


, : Primary screening of viral inhibitors in tissue culture. Khimiko Farmatsevticheskii Zhurnal 12(11): 30-34

Antiviral activity of 44 compounds was reported with respect to arbovirus, poxvirus, herpes virus L2 (in chick embryo fibroblasts), adenovirus type 3, parainfluenza type 3 virus, echovirus 6 (in human skin-muscle tissue), influenza A2 virus (in chick embro chorioallantoic membrane cultures), coliphages f2 and T2 (in Escherichia coli cells) and fixed rabies virus (in white mice).

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Moulin, Hé.R.; Seuberlich, T.; Bauhofer, O.; Bennett, L.C.; Tratschin, J-Duri.; Hofmann, M.A.; Ruggli, N., 2007: Nonstructural proteins NS2-3 and NS4A of classical swine fever virus: essential features for infectious particle formation. The nonstructural protein NS2-3 of pestiviruses undergoes tightly regulated processing. For bovine viral diarrhea virus it was shown that uncleaved NS2-3 is required for infectious particle formation while cleaved NS3 is essential for genome repli...

Hetzel, D.J.S.; Nicholas, F.W., 1976: Heritability of some growth characters in mice at different feeding levels. Feed intake and conversion efficiency were measured between 21 and 42 days of age in mice from a random-mating laboratory population on 4 different dietary levels (ad lib. and 90, 80 and 70% of ad lib. consumption). There were approx. 350 mice per...

Morlin C., 1980: The effect of captopril on the serum level of prolactin. Ircs (international Research Communications System) Medical Science Library Compendium: 217

Matsuda, Noboru, 1956: Effects of serum Ca decreasing substance extracted from human urine upon calcification and development figure of rabbit dentine. Crude and purer Ca-decreasing substances from human urine remarkably accelerate dentine calcification in the rabbit. The crude one is inhibitory in a large dose, and accelera-tive in a small dose. The pure one is more significantly accelerative th...

Wang, Z.; Sun, X.; Zhao, Y.; Guo, X.; Jiang, H.; Li, H.; Gu, Z., 2015: Evolution of gene regulation during transcription and translation. Understanding how gene regulation evolves is a key area in the current evolutionary field. Gene regulation occurs at various levels. Previous work on the evolution of gene regulation has largely focused on gene transcription. In this study, we use...

Shibukawa A.; Akai H., 1981: Effects of manta on the silk production of a silkworm race producing heavy cocoon shells. Manta [an insect growth regulator] was administered to determine its effects on silk production in a silkworm race characterized by heavy cocoon shells. In the control animals the average coccoon shell weight of both female and male was 72.4 cg. I...

Dong, Y.J.; Wadsworth, R.M., 1986: Effects of drugs that activate or inhibit calcium channels on contraction of the aorta from hypertensive rabbits. A comparison was made of contractile responses of aortic rings isolated from rabbits with perinephritis hypertension and sham-operated rabbits. Contraction was elicited by potassium, noradrenaline or 11,9-epoxymethano PGH2 (a thromboxane A2 mimeti...

Lorie, I.I.; Poddubnaia, I.V., 1970: Characteristics of uric acid metabolism in acute leukemia. Problemy Gematologii i Perelivaniia Krovi 15(12): 24-27

Harbron S.; Smith B.W.; Lilly M.D., 1986: Two liquid phase biocatalysis epoxidation of 1 7 octadiene by pseudomonas putida. Production of 7,8-epoxy-1-octene from 1,7-octadiene by non-growing Pseudomonas Putida PpG6 in a two-liquid phase reaction has been characterized. The measured activity of the bacteria depended on the ratio of the organic and aqueos phases and the...

Roche, R.; Salazar, P.; Martín, M.; Marcano, F.; González-Mora, J.L., 2012: Simultaneous measurements of glucose, oxyhemoglobin and deoxyhemoglobin in exposed rat cortex. The present work addresses the simultaneous monitoring of hemoglobin and glucose consumption in rat somatosensory cortex in vivo. We propose a method which combines two techniques: 2-dimensional optical imaging and an amperometric microbiosensor....