+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Primary structure of gamma subunit precursor of calf muscle acetylcholine receptor deduced from the complementary dna sequence

, : Primary structure of gamma subunit precursor of calf muscle acetylcholine receptor deduced from the complementary dna sequence. European Journal of Biochemistry 143(1): 109-116

Clones carrying c[complementary]DNA sequences for the .gamma. subunit precursor of the acetylcholine receptor from calf skeletal muscle were isolated. Nucleotide sequence analysis of the cloned cDNA revealed the primary structure of this polypeptide, which consists of 519 amino acids including a hydrophobic prepeptide of 22 amino acids. The .gamma. subunit of the calf muscle acetylcholine receptor, like the .alpha. subunit of the calf as well as the human muscle receptor, shares features characteristic of all 4 subunits of the Torpedo californica electroplax receptor, such as the putative disulfide bridge corresponding to that in the .alpha. subunit proposed as being in close proximity to the acetylcholine binding site and the 4 putative, hydrophobic transmembrane segments M1-M4. Thus, the calf .gamma. subunit molecule apparently exhibits the same transmembrane topology as proposed for the fish receptor subunits. The degree of sequence homology between the calf and Torpedo .gamma. subunits (56%) is lower than that between the .alpha. subunits of the 2 spp. (81%). Some regions of the .gamma. subunit molecule, including the region encompassing the putative disulfide bridge and the region containing the putative transmembrane segments M1, M2 and M3, are relatively well conserved between the 2 spp.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006184877

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

McNertney, D. C., 2004: The Paradigm SVA system. This paper discusses the Paradigm Seed Lot Vigour Assessment system which is designed to meet and often exceed the guidelines of the Association of Official Seed Analysts on seedling growth and evaluation (seedling vigour and seedling growth rate...

Gudas, C.J., 1977: Mechanism and reconstruction of pes cavus. Many important factors are involved in the surgical treatment of pes cavus. Among these factors are the location of the deformity--frontal, sagittal, or transverse planes--and whether there is an associated muscle weakness. Biomechanical analysis...

Sylvester, Olive, 1943: List of remedies to relieve irritation of skin. A compilation of chemicals used by florists to counteract irritations caused by handling ferns, primula, narcissus, chrysanthemum, and poison ivy.

Madden, E., 1983: Brucellosis. A history of the disease and its eradication from cattle in Great Britain. The history of bovine brucellosis and its control in the UK is recounted from the first reports of the disease in the mid-19th century to its eradication in 1981. The programme of eradication was officially completed on 1st November 1981 with the...

Singh M.M.; Talibudeen O., 1971: Potassium aluminum exchange equilibria in acid soils of malaya and the use of thermodynamic functions to predict the release of nonexchangeable potassium in soil to plants. Kanwar, J S (Ed ) International Symposium on Soil Fertility Evaluation, Vol I Xvi+1117p Illus Indian Society Of Soil Science, Indian Agricultural Research Institute: New Delhi, India

VIANNA.J.B.; HERLINGER.E., 1953: Streptomycin in the treatment of simple chancroid; attempt at treatment with dihydrostreptomycin. Arquivos de Cirurgia Clinica E Experimental 37(311): 3-6

Enghild, J.J.; Salvesen, G.; Brew, K., 1989: Interaction of human rheumatoid synovial collagenase (matrix metalloproteinase 1) and stromelysin (matrix metalloproteinase 3) with human a2-macroglobulin and chicken ovostatin. Binding kinetics and identification of matrix metalloproteinase cleavage sites. The Journal of Biological Chemistry 264: 79-85

Bronsted, H. V., 1931: Bygningen af snuden og ansigtsmuskulaturen hos nogle Pinnepedier med saerligt hensyn till oppustningssaekken hos klapmydsen. Kongelige Danske Videnskabernes Selskabs Skrifter 9: 4(no. 2: 43-85

Arzumanjan, E. A., 1956: Fundamental problems in the formation of cattle breeds. Methods used in forming breeds and breed groups are described. The characters of 6 recognized new breeds in the U.S.S.R. are given as well as the characteristics of progeny obtained from established breeds crossed with East Friesians, Shorthorns o...

Waloga, G., 1983: Effects of calcium and guanosine-3',5'-cyclic-monophosphoric acid on receptor potentials of toad rods. Membrane potential was recorded intracellularly from rod outer segments in the isolated retina of Bufo marinus. The composition of the solution flowing over the exposed receptor side of the retina was changed rapidly and ionophoretic injections we...