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Production of acetic acid by Clostridium thermoaceticum in batch and continuous fermentations



Production of acetic acid by Clostridium thermoaceticum in batch and continuous fermentations



Biotechnology and Bioengineering 28(5): 678-683



Batch and continuous fermentations with Clostridium thermoaceticum (ATCC 39073) using automatic pH control were conducted. The value of mu(max) obtained from batch fermentation was about 0.14 h(-1); acetate yield, which was both growth and non-growth associated, was about 2 mole of acetic acid/mole of glucose, compared with a theoretical maximum value of 3. This low yield, compared with literature data, may be explained by glucose loss through a combination of degradation routes. Continuous fermentation could be sustained for 1600 h or more without contamination problems. Continuous fermentation at high dilution rates indicates that mu(max) may be well above 0.17 h(-1) when fresh feed medium is used. Acetate yields in continuous fermentation were about 77% of theoretical or 2.3 mole of acetic acid/mole of glucose.

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Accession: 006190842

Download citation: RISBibTeXText

PMID: 18555379

DOI: 10.1002/bit.260280507



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