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Prognosis in acquired aplastic anemia a multi variate statistical analysis of 80 cases



Prognosis in acquired aplastic anemia a multi variate statistical analysis of 80 cases



Scandinavian Journal of Haematology 26(4): 321-329



Prognostic factors were studied in 80 patients with aplastic anemia. The most important and easily obtainable individal variables, isolated in a previous univariate statistical analysis, were placed in a linear logistic regression model. A prognostic formula was derived containing the following 4 variables, in decreasing order of significance: reticulocytes, interval from onset of symptoms to 1st visit, mean red cell volume and platelets. The prognostic formula permits an estimate of the probability of death within 3 mo. from the 1st visit. Its usefulness in several clinical situations, especially those related to bone marrow transplantation, is illustrated.

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Accession: 006195289

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PMID: 7038844


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