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Prospective studies on hodgkins disease in ibadan nigeria a preliminary report


African Journal of Medicine & Medical Sciences 14(1-2): 37-44
Prospective studies on hodgkins disease in ibadan nigeria a preliminary report
A preliminary report of a prospective study of Hodgkin's disease (HD) is provided, based on clinical and laboratory findings on 21 patients seen between July 1978 and Dec. 1979 at the University College Hospital (UCH), Ibadan [Nigeria]. Staging procedure was minimized to relatively simple surgical procedures like lymphangiography and percutaneous biopsy. Staging laparotomy was performed only in 1 case. Female patients were significantly older than males (P < 0.05). Patients with lymphadenopathy were significantly older than those without (P < 0.05), while those with systemic symptoms were significantly younger than those without. Eighteen (86%) of the patients presented with stage IV disease while 12 (57%) had the unfavorable histologic mixed cellularity or lymphocyte depleted variants. Systemic symptoms were present in 16 (76%) of patients. Fifty-three % of adequately treated patients showed poor response to chemotherapy. The prognosis of HD in Ibadan is on the whole unfavorable. A delineation of the prognostic factors is indicated.


Accession: 006206133



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