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Proton and hydrogen nmr studies of water in gamma irradiated phosphatidylcholine multilamellar liposomes



Proton and hydrogen nmr studies of water in gamma irradiated phosphatidylcholine multilamellar liposomes



International Journal of Radiation Biology & Related Studies in Physics Chemistry & Medicine 48(1): 117-126



1H- and 2H-NMR studies of .gamma.-irradiation-induced variations in the dynamic structure and proportional amounts of free, trapped and bound water species in multilamellar liposomes are reported and discussed. Bound water is shown to increase with dose and to be present in 2 different structural states. A dose-dependent decrease in the 1H-NMR relaxation times of bound water following .gamma.-irradiation is reported. Variations are suggested as being due to large scale changes at the bilayer surface.

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Accession: 006215369

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