Purification of some drugs by directed sublimation

Dugacheva, G.M.; Saryan, L.A.; Popkov, V.A.; Gladun, E.P.

Farmatsiya 37(4): 44-48

1988


ISSN/ISBN: 0367-3014
Accession: 006233644

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Abstract
An alternative method for directed sublimation was developed to purify amidopyrine, antipyrine, nicotinic acid, isoniazid, and phthivazid. Optimal conditions for cleaning were proposed for each substance. Purification gave rise to substances having high (99.95-99.7 mol.%) purity in a 95-70% yield.