Quantitation activated complement c 1r activated complement c 1s activated complement c 1 inactivator complexes by electro immunoassay
Laurell A B.; Martensson, U.; Sjoholm, A.G.
Acta Pathologica et Microbiologica Scandinavica Section C Immunology 87(1): 79-82
ISSN/ISBN: 0304-1328 Accession: 006239165
A method for measuring complexes of C.hivin.1r[r fragment of activated complement component 1]-C.hivin.1s-C.hivin.1 IA [inactivator] in normal and pathological human sera was developed. Electroimmunoassay was applied. The antigenic and electrophoretic properties of the known C1 subcomponent complexes in serum were beneficial. The concentrations of C.hivin.1r-C.hivin.1s-C.hivin.1 IA complexes of 20 normal sera were determined. Storage of serum at room temperature markedly increased the values over those obtained from fresh specimens; freezing and thawing do not influence the results.