+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Radial keratotomy. Effect on cornea and aqueous humor physiology in the rabbit

Radial keratotomy. Effect on cornea and aqueous humor physiology in the rabbit

Archives of Ophthalmology 101(3): 479-481

Radial keratotomy may cause anatomical damage to the rabbit corneal endothelium. To determine if physiological and functional alterations occur, radial keratotomy was performed on rabbit corneas using eight incisions with sparing of a 3.5-mm central pupillary area. Cornea endothelial membrane permeabilities were determined at various times up to ten weeks following the procedure using simultaneous flux determinations of tritiated inulin and dextran labeled with radioactive carbon on isolated corneas. At all times after radial keratotomy, there was no probable physiologically important change in corneal endothelial permeability to either of the labeled compounds. Fluorophotometry performed in a second group of animals at varying intervals following radial keratotomy showed no probable physiologically important change in endothelial fluorescein permeability. Aqueous humor turnover rate was reduced 16% and 29% at one week and nine to ten weeks, respectively, following radial keratotomy.

(PDF emailed within 1 workday: $29.90)

Accession: 006248582

Download citation: RISBibTeXText

PMID: 6830508

Related references

Influence of radial keratotomy on endogenous hyaluronan in cornea and aqueous humour. Refractive & Corneal Surgery 9(5): 358-365, 1993

An ultrastructural study of the rabbit cornea after radial keratotomy. Chinese Journal of Ophthalmology 29(5): 296-298, 1993

Effects of beta amino propionitrile on the rabbit cornea after radial keratotomy. Investigative Ophthalmology & Visual Science 23(3 SUPPL): 29, 1982

Endothelial damage after anterior radial keratotomy. An electron microscopic study of rabbit cornea. Archives of Ophthalmology 99(12): 2151-2158, 1981

Effect of cryosurgery of the ciliary body on acid-base equilibrium of the aqueous humor after alkali burn of the rabbit cornea. Klinika Oczna 90(1): 9-11, 1988

Penetration of topical cyclosporine into the rabbit cornea, aqueous humor, and serum. Archives of Ophthalmology 103(1): 101-102, 1985

Experimental research on the effect of radial keratotomy on th e mechanical properties of the cornea. Oftalmologicheskii Zhurnal: 54-58, 1990

The concentration of Benzalkonium chloride in aqueous humor on the deepithelized area of rabbit cornea. IOVS 41(4): S901, March 15, 2000

Determination Of The Free Amino Acid Content Of The Cornea And Aqueous Humor Of The Rabbit. Szemeszet 100: 217-220, 1963

Studies of aqueous humor dynamics: Part I. Effect of intravenous administration of beta blocking agent (propranolol) on tension lowering mechanism of rabbit eye as observed by determination of fluorescein concentration curve of aqueous humor. Chinese Journal of Ophthalmology 16(2): 113-116, 1980

The effect of radial keratotomy on the corneal endothelium at 10 years after surgery in the prospective evaluation of radial keratotomy study. Investigative Ophthalmology & Visual Science 37(3): S319, 1996

Continuous flow contact lens delivery of gentamicin to rabbit cornea and aqueous humor. Journal of Ocular Pharmacology 8(4): 317-323, 1992

A novel continuous flow contact lens for delivery of gentamicin to rabbit cornea and aqueous humor. Investigative Ophthalmology & Visual Science 31(4 ABSTR ISSUE): 558, 1990

Study of the effect of hydrophilic gel contact lenses on the cornea part 1 lactic acid in the cornea and aqueous humor and cornea hydration after application of contact lenses geltakt in rabbits. Ophthalmologica 159(4-6): 398-406, 1969

Distribution of dihematoporphyrin in rabbit cornea, iris, aqueous humor and plasma after topical vs intravenous administration. Investigative Ophthalmology & Visual Science 36(4): S551, 1995