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Radix salviae miltiorrhizae rhizoma corydalis decoction and nicotinic acid solution iontophoresis to the precordium in treatment of angina pectoris a preliminary report

, : Radix salviae miltiorrhizae rhizoma corydalis decoction and nicotinic acid solution iontophoresis to the precordium in treatment of angina pectoris a preliminary report. Chinese Medical Journal (Peking) (3): 166-168

Cases of angina pectoris (36) treated by Radix Salviae (Salvia root) miltiorrhizae-Rhizoma Corydalis [Corydalis rhizome] decoction and nicotinic acid solution iontophoresis over the precordium and 30 control cases treated routinely with hydolipidemic agents and vasodilators were studied. Patients in both groups had angina pectoris and ECG consistent with coronary heart disease and were similar with respect to duration of illness, age, symptoms and signs, complications and serum cholesterol level. Consecutive treatments (15), of 15-20 min each constituted a course of treatment; each patient received 2 or more courses. Effective results were obtained in 52.8% of the cases in the iontophoresis group and 23.3% in the control group. Iontophoresis with Radix Salviae miltiorrhizae-Rhizoma Corydalis decoction is useful in the treatment of angina pectoris in coronary heart disease. The severity of angina pectoris influenced treatment; results were more satisfactory in mild cases than in moderately severe cases. Age and duration of illness were irrelevant factors. The mechanism of iontophoresis with traditional drugs in the treatment of angina pectoris is discussed in conjunction with a review of relevant Chinese and foreign medical literature. Better therapeutic effects depend on a combination of direct passage through the segmental skin and viscera reflex and the circulation-promoting, analgesic action of traditional drugs.

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