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Recent trends in incidence and mortality rates for leukemias and in survival rates for childhood acute lymphocytic leukemia in upstate new york usa

, : Recent trends in incidence and mortality rates for leukemias and in survival rates for childhood acute lymphocytic leukemia in upstate new york usa. Cancer 57(9): 1850-1858

Analysis of mortality rates for all childhood (age < 20 years) leukemias in upstate New York showed declines between 1969-1971 and 1978-1978 for ages 0-4 and 5-9 yers, while data from a population-based cancer registry for a population of about 10.5 million indicated no decline in incidence rates. Survival rates were examined for 552 children diagnosed with acute lymphocytic leukemia (ALL) in 1973-1980 at < 15 years of age. There was some evidence for improvement in survival rates over these years of diagnosis, especially among children diagnosed at ages 1-4 and 10-14 years. Hazard rates increased among cases (especially males) diagnosed in 1979 and 1980, however, and this finding requires confirmation from other studies; the possible effect of influenza epidemics also should be explored. Only one confirmed second primary cancer, a rhabdomyosarcoma of the eye, was ascertained (as of the end of 1983), but longer follow-up is needed on children with ALL.

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