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Recovery from inhibition of transcription in gamma irradiated euglena gracilis cells



Recovery from inhibition of transcription in gamma irradiated euglena gracilis cells



Biochimica et Biophysica Acta 697(1): 14-19



Transcriptional activity was inhibited with low doses of .gamma.-irradiation which did not cause the death of cells, but induced the delay of cell division in the unicellular alga Euglena. The incorporation of [14C]uracil into cells was inhibited to about 50% of nonirradiated cells immediately after 3 krad irradiation. The suppressed transcriptional activity was gradually recovered after irradiation. At about 12 h post-irradiation, the rate of incorporation of [14C]uracil recovered to that of nonirradiated cells. The synthesis of rRNA was inhibited immediately after 3 krad irradiation, but it was recovered within 12 h after irradiation. The synthesis of cytosol rRNA precursor was more strongly inhibited than that of other cytosol rRNA. The synthesis of cytoplasmic organelle rRNA was also inhibited and recovered after 3 krad irradiation.

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Accession: 006273940

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