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Regulation of glucose 6 phosphate dehydrogenase ec 1.1.1.49 activity in primary rat hepatocyte cultures


, : Regulation of glucose 6 phosphate dehydrogenase ec 1.1.1.49 activity in primary rat hepatocyte cultures. Biochemical and Biophysical Research Communications 96(2): 748-755

The glucose-6-P dehydrogenase specific activity in rat hepatocytes increases approximately 10-fold when the cells are placed into culture for 3 days. The induction requires insulin with maximum enzyme levels occurring at 10-7 M. Pulse-labeling experiments revealed a 10-fold increase in the enzyme's relative rate of synthesis after only 8 h in culture.

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Tamemoto, Hiroyuki; Kadowaki, Takashi; Tobe, Kazuyuki; Yagi, Takeshi; Sakura, Hiroshi; Hayakawa, Takaki; Terauchi, Yasuo; Ueki, Kohjiro; Kaburagi, Yasushi; Satoh, Shinbou; Sekihara, Hisahiko; Yoshioka, Shinji; Horikoshi, Hiroyoshi; Furuta, Yasuhide; Ikawa, Yoji; Kasuga, Masato; Yazaki, Yoshio; Aizawa, Shinichi, 1994: Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Insulin receptor substrate-1 (IRS-1) is the major substrate of insulin receptor and IGF-1 receptor tyrosine kinases; it has an apparent relative molecular mass of 160-190,000 (M-r, 160-190K) on SDS polyacrylamide gel. Tyrosine-phosphorylated IRS-1...

Ernst W. G., 1988: Metamorphism of the Western Cordillera, post-Archean crustal growth and terrane accretion, conterminous U.S.A. Proceedings of the International Conference on Basement Tectonics 8: 24

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Hagerup, H., 1934: Controlled grazing for the different methods of cultivation employed in the conversion of grass-bog into pasture. Trials were conducted at Maeresmyra, Norway, from 1924-33 with different methods of cultivation in the conversion of grass bog into pasture. The yield was controlled by grazing with young cattle. The methods of cultivation were (a) complete (ploug...

Jaworek D., 1974: New immobilization techniques and supports. Pye, E Kendall And Lemuel B Wingard, Jr Enzyme Engineering, Vol 2 Conference, Henniker, N H , U S A , Aug 5-10, 1973 Xiv+470p Illus Plenum Press: New York, N Y , U S A ; London, England Isbn 0-306-35282-6 105-114

Lapshina, E. I., 1963: Geobotanical regionalization of the southeast area of the Western Siberian lowland. The author separates territorial units on the basis of the nature of the vegetation and of the natural conditions affecting the formation and development of the plant cover which are characteristic of the whole complex. The southeast area of the W...

Murphy Brian W.; Eldridge David J.; McKane Dermont J.; Gray Jonathon M., 2000: Soil landscapes of New South Wales.; 2. Pages 150-165:

Dahse I.; Schnabl H.; Hampp R.; Michalke B.; Ziegler H., 1987: Tentoxin affects light induced opening of stomata and gcp swelling by inhibition of photophosphorylation. International Botanical Congress Abstracts 17: 89

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