EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Regulation of glutamate oxidation in mitochondria of xenopus laevis oocytes


Comparative Biochemistry & Physiology B 66(1): 1-12
Regulation of glutamate oxidation in mitochondria of xenopus laevis oocytes
Glu is metabolized mainly by transamination to Asp. Reductive deamination by GDH [glutamate dehydrogenase] is found in 1/3 of all Glu that disappeared. Glu transamination of Ala is negligible. NADH and 2-oxoglutarate concentrations involve a glutamate-stat by acting both on the GDH system and on the GOT-MDH [glutamate oxaloacetate transaminase-malate dehydrogenase] coupled system: the extremely low equilibrium constants of these 2 systems support Glu formation. Equilibrium constant of the GOT-MDH coupled system is 4.05 .times. 10-5 at 25.degree. C, pH 7.4. Oxaloacetate available, MDH competes with the respiratory chain for NADH. Malic enzyme (NAD+) promoting male oxidation contributes to NADH supply involved in Glu metabolization control.

Accession: 006288107

DOI: 10.1016/0305-0491(80)90077-2

Download PDF Full Text: Regulation of glutamate oxidation in mitochondria of xenopus laevis oocytes



Related references

Aerobic and anaerobic oxidation of fumarate in mitochondria of the oocytes of Xenopus laevis. La Ricerca Scientifica 38(6): 564-567, 1968

Modulation of the citrate cycle in mitochondria of Xenopus laevis oocytes and biorhythms. I. Characteristics of "holocoherent" mitochondria. Acta Embryologiae Experimentalis: 13-38, 1978

Electrogenic L-glutamate uptake in Xenopus laevis oocytes expressing a cloned rat brain L-glutamate/L-aspartate transporter (GLAST-1). Journal of Biological Chemistry 268(20): 14594-6, 1993

Mitochondria DNA synthesis in oocytes of Xenopus laevis. Experimental Cell Research 119(2): 414-418, 1979

DNA topoisomerase I from mitochondria of Xenopus laevis oocytes. European Journal of Biochemistry 118(2): 407-415, 1981

Enzymatic characteristics of the mitochondria of xenopus laevis oocytes. Acta Embryologiae Experimentalis (2): 115-122, 1975

Enzymatic aspects of the mitochondria of Xenopus laevis oocytes. Acta Embryologiae Experimentalis: 115-122, 1975

The number of mitochondria in Xenopus laevis ovulated oocytes. Cell Differentiation 16(2): 139-143, 1985

Endogenous L-glutamate transport in oocytes of Xenopus laevis. Biochimica et Biophysica Acta 1066(1): 14-20, 1991

Characterization of DNA-protein complexes from the mitochondria of Xenopus laevis oocytes. Experimental Cell Research 157(1): 207-217, 1985