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Regulation of glutamine synthetase ec 6.3.1.2 by regulatory protein p i i in klebsiella aerogenes mutants lacking adenylyl transferase


Journal of Bacteriology 146(2): 740-745
Regulation of glutamine synthetase ec 6.3.1.2 by regulatory protein p i i in klebsiella aerogenes mutants lacking adenylyl transferase
A mutation in K. aerogenes causing production of an altered PII regulatory protein which stimulates overadenylylation of glutamine synthetase [EC 6.3.1.2] and also prevents its derepression was combined with mutations abolishing the activity of adenylyltransferase. PII apparently plays a role in the regulation of the level of glutamine synthetase which is independent of its interaction with adenylyltransferase.


Accession: 006288129



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