+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Regulation of glycogen synthase activity in muscle by a carboxyl terminal part sequence of human growth hormone

, : Regulation of glycogen synthase activity in muscle by a carboxyl terminal part sequence of human growth hormone. Archives of Biochemistry & Biophysics 224(1): 365-371

The synthetic peptide hGH [human growth hormone] 177-191, corresponding to the last 15 residues at the carboxyl terminus of pituitary growth hGH, promotes the conversion of glycogen synthase a to glycogen b in muscle. When injected, the peptide produced inactivation of glycogen synthase phosphatase activity in rat skeletal muscle. The time course of phosphatase inactivation was closely correlated with that for glycogen synthase. The peptide had no effect either on muscle 3',5'-cAMP levels or on synthase kinase activity. These results can be explained in terms of a dynamic cycle of interconversion of synthase between active and inactive forms, by the simultaneous action of synthase kinases and synthase phosphatases. A decrease in the ratio of phosphatase to kinase activity would result in a decrease in the steady-state level of synthase a activity.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006288179

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Anonymous, 2011: Protection of dichlorvos induced oxidative stress and nigrostriatal neuronal death by chronic Coenzyme Q1 pretreatment. Numerous epidemiological studies have shown an association between pesticide exposure and increased risk of developing Parkinson's diseases. Oxidative stress generated as a result of mitochondrial dysfunction has been implicated as an importa...

Cheng K.M.; Shoffner R.N.; Gelatt K.N.; Gum G.G.; Otis J.S.; Bitgood J.J., 1980: An autosomal recessive blind mutant in the chicken. A type of blindness due to lack of rods and cones in the retina is controlled by a single autosomal recessive gene, rc. The mutation was first identified in the second generation decendents of a male carrying an ethyl methanesulfonate (EMS) induce...

Heller, J.; Piechowska, MJ., 1971: Changes in amylase activity during metamorphosis of the hawk moth Celerio euphorbiae L. (Lepidoptera). Bulletin Acad. pol. Sci. (Ser. Sci. Kumamoto J Sci (Biol): 194: 229-235

Yang, H. W.; Gunasekaran, S., 2004: Comparison of temperature distribution in model food cylinders based on Maxwell's equations and Lambert's law during pulsed microwave heating. Two-percent agar gel cylinders were heated using pulsed and continuous microwave energy. Temperature distribution inside the sample was measured and compared with numerical predictions based on the Lambert's law and Maxwell's equations....

Cerda, B. De-La; Diaz-Quintana, A; Navarro, Ja; Hervas, M; Rosa, Ma-De-La, 1999: Site-directed mutagenesis of cytochrome c6 from Synechocystis sp. PCC 6803. Journal of biological chemistry 274(19): 13292-13297

Sinclair, A. N., 1964: Surface spraying and dusting as means of controlling external parasites of sheep. For the control of keds and body lice sheep must be treated within 24 hours of shearing. Different applicators require different concentrations of insecticide. Too rapid transit of sheep through the machine gives an inadequate deposit of insectici...

Brown A.J.P.; Bertram G.; Feldmann P.J.F.; Peggie M.W.; Swoboda R.K., 1991: Codon utilization in the pathogenic yeast candida albicans. Nucleic Acids Research 19(15): 4298

Hegner B.; Pilleri G., 1968: Note on the morphology of the eye of hippopotamus amphibius and choeropsis liberiensis mammalia artiodactyla hippopotamidae with special consideration of the tapetum lucidum fibrosum and the schlemms canal horse primate. Acta Anatomica 69(3): 458-461

Fraser K.J.; Mckenzie I.; Mcpherson J.; Ruddy S., 1975: Complement c 2 deficiency and connective tissue disease a family study. Australian & New Zealand Journal of Medicine 5(5): 499

Youssef, Adel A.; Valdez, Rudolfo; Elkasabany, Abdala; Srinivasan, Sathanur R.; Berenson, Gerald S., 2002: Time-course of adiposity and fasting insulin from childhood to young adulthood in offspring of parents with coronary artery disease: The Bogalusa Heart Study. PURPOSE: Obesity and the attendant insulin resistance/hyperinsulinemia related to coronary artery disease (CAD) morbidity and mortality are well documented. However, information is lacking on the time-course relation of adiposity and fasting insul...