+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Regulation of heliomycin biosynthesis by a source of carbon

, : Regulation of heliomycin biosynthesis by a source of carbon. Antibiotiki i Meditsinskaya Biotekhnologiya 30(4): 264-271

The effect of different C sources on the biosynthesis of heliomycin by Streptomyces olivocinereus 11-98 was studied. Inverse relationship between the culture growth rate and the biosynthesis of heliomycin in the media with different sugars was shown. Arabinose and glucose provided the highest culture growth rate, while the levels of the antibiotic biosynthesis were the lowest. With the use of lactose, the culture growth rate was the lowest and the antibiotic biosynthesis level was the highest. The level of the antibiotic biosynthesis was determined by the culture growth rate but also by the nature of the C source. With the use of glucose repression of heliomycin biosynthesis was much lower than that with use of arabinose, while the culture growth rates were similar. Addition of glucose to the medium with lactose resulted in increasing of the antibiotic biosynthesis as long as the glucose concentration in the medium increased. Glycerol was the most favorable C source for the biosynthesis of heliomycin; it also provided a comparatively high rate of the culture growth. Arabinose inhibited antibiotic synthesis in the medium with glycerol and the inhibition level rose with an increase in the arabinose concentration. It is suggested that regulation of heliomycin biosynthesis is of the glucose effect type.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006288332

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Aizen, M. A.; Basilio, A., 1998: Sex differential nectar secretion in protandrous Alstroemeria aurea (Alstroemeriaceae): is production altered by pollen removal and receipt?. We examined diurnal and nocturnal nectar secretion across sexual stages in protandrous Alstroemeria aurea, a bumble bee-pollinated herb with long-lived flowers native to the southern Andes. We found the following patterns: (1) most nectar was pr...

Hashiguchi K., 1991: Inexpedience of the non-associated flow rule. International Journal for Numerical and Analytical Methods in Geomechanics 15(10): 753-756

Paganelli R.; Levinsky R.J.; Aiuti F., 1982: Interleukin 2 production is impaired in patients with primary t cell defects. Lymphocytes from normal subjects and patients with primary immunodeficiencies were tested for in vitro mitogenic responses with and without the addition of interleukin 2[IL-2]-containing supernatants. Cells from normals and hypogammaglobulinemic p...

Pyatnitskii, S. S., 1960: Interspecific oak hybrids Distant Hybridization of Plants and Animals. Data Missing : 177-208

Perumal, D., 2001: Microencapsulation of ibuprofen and Eudragit(R) RS 100 by the emulsion solvent diffusion technique. The emulsion solvent diffusion was employed to prepare modified release microspheres of ibuprofen. The technique was optimised for the following processing variables: the absence/presence of baffles in the reaction vessel, agitation rate and dryin...

Ness, R. B.; Harris, T.; Cobb, J.; Flegal, K. M.; Kelsey, J. L.; Balanger, A.; Stunkard, A. J.; D'agostino, R., 1992: Gravidity and cardiovascular disease. American Journal of Epidemiology 136(8): 984-985

Chan, David Y.; Jeffs, Robert D.; Gearhart, John P., 1999: Determinates of continence after bladder neck reconstruction in the bladder exstrophy population. Pediatrics 104(3 PART 3): 823-824, Sept

Lemos de Castro, A., 1958: Revisao do genero Benthana Budde-Lund,1908(Isopoda-Oniscidae). Arquivos do Museu Nacional Rio de Janeiro, 46: 85-118

Martinez, Gabriel; Ropero, Claudia; Funes, Andrea; Flores, Erica; Landa, Adriana I.; Gargiulo, Pascual A., 2002: AP-7 into the nucleus accumbens disrupts acquisition but does not affect consolidation in a passive avoidance task. The effect of the blockade of N-methyl-D-aspartic acid (NMDA)-type glutamatergic receptors in the nucleus accumbens septi (Acc) during different phases of a passive avoidance task (step-through paradigm, two chambers) of learning was studied in ma...

Anonymous, 2012: Mutant huntingtins interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntingtons disease. The purpose of this study was to investigate the link between mutant huntingtin (Htt) and neuronal damage in relation to mitochondria in Huntington's disease (HD). In an earlier study, we determined the relationship between mutant Htt and mit...