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Regulation of hemogenesis and immunogenesis with low molecular weight and macro molecular metallo complexes the iron effect on the hemopoietic stem cells and t b cooperation in immune response


, : Regulation of hemogenesis and immunogenesis with low molecular weight and macro molecular metallo complexes the iron effect on the hemopoietic stem cells and t b cooperation in immune response. Immunologiya (1): 47-50

The influence of Fe ions on the immune response to sheep red cells, the cooperation of T- and B-lymphocytes, and the migration, proliferation and differentiation of stem cells were studied in young and old intact mice, and in old thymectomized mice. The Fe ions produced no effect on antibody production at the level of the whole body, but they significantly intensified the process of T- and B-lymphocyte cooperation. Young mice showed Fe-intensified migration and proliferation of stem cells with their differentiation being shifted towards erythropoiesis. In old intact and old thymectomized mice Fe ions stimulated both erythro- and granulopoiesis.

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