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Regulation of hepatic 3 hydroxy 3 methyl glutaryl coenzyme a reductase ec 1.1.1.34 and cholesterol synthesis






Journal of Biological Chemistry 246(10): 3210-3216

Regulation of hepatic 3 hydroxy 3 methyl glutaryl coenzyme a reductase ec 1.1.1.34 and cholesterol synthesis



Accession: 006288373



Related references

Balasubramaniam, S.; Goldstein, J.L.; Brown, M.S., 1977: Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3 hydroxy 3 methyl glutaryl coenzyme a synthase ec 4.1.3.5 and 3 hydroxy 3 methyl glutaryl coenzyme a reductase ec 1.1.1.34 activities. Activities of cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase [3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating), EC 4.1.3.5] and microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase [mevalonate:NADP+ oxidoreduc...

Bergstrom J.D.; Wong G.A.; Edwards P.A.; Edmond J., 1983: Regulation of hepatic acetoacetyl coenzyme a synthetase in cholesterol synthesis synchrony with 3 hydroxy 3 methyl glutaryl coenzyme a reductase. Federation Proceedings 42(7): ABSTRACT 1901

Volpe, J.J.; Obert, K.A., 1981: Coordinate regulation of cholesterol synthesis and 3 hydroxy 3 methyl glutaryl coenzyme a synthase ec 4.1.3.5 but not 3 hydroxy 3 methyl glutaryl coenzyme a reductase ec 1.1.1.34 in c 6 glia. The effects on cholesterol biosynthesis of growth of cultured [rat] C-6 glial cells in serum-free medium .+-. supplementation with linoleic or linolenic acid were studied. Markedly higher activities of 3-hydroxy-3-methylglutaryl CoA reductase (HMG...

Bergstrom J.D.; Wong G.A.; Edwards P.A.; Edmond J., 1983: Cholesterol synthesis from acetoacetate and the regulation of hepatic acetoacetyl coenzyme a synthetase by modulators of 3 hydroxy 3 methyl glutaryl coenzyme a reductase activity. American Heart Association Monograph (101): III-289

Sipat A.B.; Sabine J.R., 1979: Membrane mediated control of 3 hydroxy 3 methyl glutaryl coenzyme a reductase and the regulation of hepatic cholesterol synthesis. Journal of Lipid Research 20(8): 1049

Anonymous, 1972: Cholesterol regulation of hepatic 3 hydroxy 3 methyl glutaryl coenzyme a reductase ec 11134

Maton P.N.; Reuben A.; Ellis H.J.; Dowling R.H., 1979: Hepatic cholesterol synthesis in chole lithiasis role of hydroxy 3 methyl glutaryl coenzyme a reductase in determining biliary cholesterol secretion. Clinical Science (London) 56(3): 15P-16P

Faust, J.R.; Chin, D.J.; Goldstein, J.L.; Brown, M.S.; Luskey, K.L., 1982: Regulation of synthesis and degradation of 3 hydroxy 3 methyl glutaryl coenzyme a reductase ec 1.1.1.34 by low density lipo protein and 25 hydroxy cholesterol in ut 1 cells. UT-1 cells are a clone of Chinese hamster overy cells that were selected to grow in the presence of compactin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase. These cells have 100- to 1,000-fold more immunoprecipitable reducta...

Arebalo R.E.; Hardgrave J.E.; Scallen T.J., 1979: The in vivo regulation of cholesterol synthesis by phosphorylation of 3 hydroxy 3 methyl glutaryl coenzyme a reductase. Federation Proceedings 38(3 PART 1): 632

Ottery F.D.; Goldfarb S., 1976: Colchicine inhibits hepatic cholesterol synthesis and microsomal 3 hydroxy 3 methyl glutaryl coenzyme a reductase activity. Federation Proceedings 35(7): 1715