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Regulation of hydrocortisone binding sites by hydrocortisone in human bone marrow fibroblasts

, : Regulation of hydrocortisone binding sites by hydrocortisone in human bone marrow fibroblasts. International Journal of Cell Cloning 4(1): 43-50

The incubation of human bone marrow fibroblasts with hydrocortisone (10(-7) M) produces a time-dependent depletion of hydrocortisone-binding sites. This effect is glucocorticoid-specific, since glucocorticoid agonists cause depletion to the same extent as hydrocortisone. After withdrawal of the hormone from the incubation medium, cells are able to replenish their complement of receptor. The existence of this down-regulation process may represent a protective mechanism against the partial proliferative inhibitory action of glucocorticoids for bone marrow fibroblasts and also a stimulus for differentiation to adipocytes.

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Accession: 006288600

PMID: 2419458

DOI: 10.1002/stem.5530040105

PDF Full Text: Regulation of hydrocortisone binding sites by hydrocortisone in human bone marrow fibroblasts

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Wood, W. A.; Fetting, R. A.; Hertlein, B. C., 1962: Gluconic dehydrogenase from Pseudomonas fluorescen. S P Colowick and N O Kaplan, Editors Methods in Enzymology Vol V p 287-291

Metz, H.J.; Kriens, O., 1969: On a new procedure for the anatomic and functional reconstruction of the soft palate in extensive resection defects. Deutsche Zahnarztliche Zeitschrift 24(7): 641-647

Gerber, Daniel T., 1986: Female Golden-fronted Woodpecker or mutant female Red-bellied Woodpecker?. American Birds 40 Summer : 3-4

Drabsch, Y.; ten Dijke, P., 2011: TGF-β signaling in breast cancer cell invasion and bone metastasis. The contribution of transforming growth factor β (TGF-β) signaling to breast cancer has been studied for more than two decades. In an early phase TGF-β may act as a tumour suppressor, while later, when cells have become resistant to its anti-mi...

Franc, A., 1954: Revision des Ellobiidae (Pulmones Basomrnatophores) de l'Archipel neo-caledonien. Bull Mus Hist nat Paris, 26(2 3: 363-369

Schmidlin, F., 2005: Nierentrauma - Behandlungsstrategien und Operationsindikationen. Most renal injuries are blunt, involve a young patient population, and are caused by motor vehicle accidents or sport injuries. Renal trauma is classified into five grades with the majority of injuries being minor. CT scan has become the standard...

Gao, L.; Wu, G-jun.; Liu, B.; Shen, M-zhi.; Pan, T-jun.; Yu, C-gong.; Wang, Q-hao.; Ru, Y.; Liu, X-ping.; Niu, T-shui.; Wang, G-dong.; Wei, M.; Li, R-xiao.; Yao, L.; Wang, H.; Li, X., 2014: Up-regulation of pVHL along with down-regulation of HIF-1α by NDRG2 expression attenuates proliferation and invasion in renal cancer cells. The majority of renal cell carcinomas (RCCs) are characterized by loss of function of the tumor suppressor gene von Hippel Lindau (VHL), which acts as ubiquitin ligase for hypoxia-inducible factor-1α (HIF-1α). In the absence of VHL, HIF-1α prot...

Kühnlein, R.P., 2011: Energy homeostasis regulation in Drosophila: a lipocentric perspective. The fruit fly Drosophila is a centenarian in research service, but a novice as an invertebrate model system for energy homeostasis research. The last couple of years, however, witnessed numerous technical advances driving the rise of this model or...

Nakamura T.; Kajihara M., 1975: Heat balance in the estuarine region. Bulletin of the Faculty of Fisheries Hokkaido University 25(4): 304-317

Jenner, P.J.; Ellard, G.A., 1987: Determination of the isoniazid metabolite monoacetylhydrazine in urine by high-performance liquid chromatography. Journal of Chromatography 415(1): 188-196