EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Regulation of immune responses via genetically restricted cellular interactions 1. augmentation of antibody responses by idiotype specific enhancing b lymphocytes


, : Regulation of immune responses via genetically restricted cellular interactions 1. augmentation of antibody responses by idiotype specific enhancing b lymphocytes. Journal of Immunology 133(6): 2882-2887

B lymphocytes obtained from BALB/c mice that had been immunized with M104E myeloma protein have an idiotype-specific enhancing activity for anti-dextran B1355S antibody responses in vivo. The enhancing cells were Thy-1-, Lyt-1-,2-, nylon wool-adherent and rabbit anti-mouse Ig (RAMG) dish adherent. The in vitro analysis described in this report also revealed that the enhancing cells had a B cell phenotype and were specifically enriched in M104E or J558 myeloma protein-coated dishes but not by irrelevant monoclonal antibodies. The significance of these B-B cell interactions were analyzed in vitro by using various Igh-1 and H-2 congeneic strains of mice. The idiotype immune B lymphocytes obtained from BALB/c and BAB-14 could enhance the anti-dextran antibody responses of BALB/c B lymphocytes in an idiotype-specific manner. C.AL-20 and CB-20 strains could not induce the idiotype-specific enhancing B cell activity in dextran-immune BALB/c B cells. The capability of enhancing B cell induction is probably related to the producibility of the respective idiotype in that strain of mice. The B cells obtained from BALB/c mice immune to the idiotype cooperated well with the dextran-immune B cells of BALB/c but not BALB.K and vice versa. Successful cooperation between those 2 types of B lymphocytes apparently requires the same MHC[major histocompatibility complex] haplotype. The roles of these genetically restricted cellular interactions in the immune system are discussed.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006288664

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Anonymous, 2011: Anurans as paratenic hosts in the transmission of Hepatozoon caimani to caimans Caiman yacare and Caiman latirostris. Prevalence of <i>Hepatozoon caimani</i> has been reported in 76% of caimans <i>Caiman yacare</i> from the Pantanal region. <i>Culex</i> (<i>Melanoconion</i>) spp. mosquitoes were recently identified...

Detrait J., 1983: The vipers of the southern portion of the central massif france external morphology and venoms. The distribution of Vipera aspis zinnikeri of southwestern France includes southern Central Massif. Morphologically, the northern species differ from the extreme southern species. Venom of V. a. zinnikeri differs profoundly from the venom of V. a....

Bialaszewicz, K., 1933: Recherches sur le metabo-lisme chimique et energetique au cours du developpement des insectes I Thermogenese pendant la periode de croissance larvaire et pendant la metamorphose de Lymantria dispar L. [long dash]The larval growth of L. dispar is discontinuous, being composed of a certain no. of waves of active assimilation, separated by periods of larval quiescence. The production of heat during post-embryonic development is synchronous with gr...

Lew V.L.; Hardy M.A.Jr; Ellory J.C., 1973: The uncoupled extrusion of sodium through the sodium pump. Biochimica et Biophysica Acta 323(2): 251-266

Church S.E.; Masson E.A.; Hanley S.P.; Sharma A.K.; Lye R.; Woodcock A.A.; Boulton A.J.M., 1988: Clinical electrophysiological and morphometric studies of peripheral nerves in patients with hypoxemia. American Review of Respiratory Disease 137(4 PART 2): 480

Burrows, Malcolm, 2006: Jumping performance of froghopper insects. The kinematics of jumping in froghopper insects were analysed from high speed sequences of images captured at rates up to 8000 s(-1). In a jump, the attitude of the body is set by the front and middle legs, and the propulsion is delivered by rapi...

HOCKADAY, T. D. R., 1964: Rapid action of hydrocortisone on the increase in blood glucose after adrenaline. Nature 203(4951): 1242-1243

Kaltsikes, P., 1983: Number of replications required for vegetable yield trials. A one-year trial with 7 aubergine cultivars was carried out in 6.6 msuperscript 2 plots with 11 plants/plot, and a 2-year trial with 8 capsicum cultivars was carried out in 5.5 msuperscript 2 plots with 11 plants/plot or in 7.5 msuperscript 2 plot...

Chris Robertson, 2011: Dangerous Margins Recovering the Stem Cells of the Psyche. The dual problem addressed here is the increasing egocentric individualism in the Western world and the blind avoidance of facing the ecological crisis. This article uses ecosystemic thinking to explore the margins of our collective predicament. I...

Folpe, Andrew, L.; Veikkola, Tanja; Valtola, Reija; Weiss, Sharon, W., 2000: Vascular endothelial growth factor receptor-3 (VEGFR-3): A marker of vascular tumors with presumed lymphatic differentiation, including Kaposi's sarcoma, kaposiform and Dabska-type hemangioendotheliomas, and a subset of angiosarcomas. Recently, a novel monoclonal antibody to vascular endothelial growth factor receptor 3 (VEGFR-3), a tyrosine kinase receptor expressed almost exclusively by lymphatic endothelium in the adult, has been shown to react with a small number of cases o...