EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Regulation of immunoglobulin synthesis by monocytes in multiple myeloma and benign monoclonal gammopathy


, : Regulation of immunoglobulin synthesis by monocytes in multiple myeloma and benign monoclonal gammopathy. Clinical and Experimental Immunology 66(3): 625-632

The distribution and regulatory function of immunoglobulin (Ig) synthesis by monocytes were assessed using several monoclonal antibodies and a cell sorter in samples from 13 patients with multiple myeloma (MM) and nine patients with benign monoclonal gammopathy (BMG). Since all of these cells were separated directly with the cell sorter, their purity and viability were greater than 98% and greater than 99%, respectively. The absolute number of lymphocytes was significantly reduced. The number of monocytes stained with non-specific esterase was within normal range in MM and BMG, as were the absolute number and the proportion of cells which reacted with OKM1 and Mo2 (OKM1+ cells and Mo2+ cells, respectively). The helper activity of monocytes in Ig synthesis stimulated with pokeweed mitogen (PWM) was impaired in MM compared with normal controls. None of these abnormalities in the distribution and regulatory function of monocytes was observed in BMG. The possible immunoregulatory mechanism of MM is discussed.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006288699

PMID: 3568450

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Andreescu I.; Papaianopol I., 1970: Biostratigraphy of the Sarmatian beds between the Milcov and Rmnicu Sarat valleys. Studii si Cercetari de Geologie, Geofizica, Geografie: Geologie. 15; 2, Pages 499-512. 1970.

Wild, A., 1994: Inter-American Tropical Tuna Commission. A two-stage sampling design is used to estimate the variances of the numbers of yellowfin in different age groups caught in the eastern Pacific Ocean. For purse seiners, the primary sampling unit (n) is a brine well containing fish from a month-ar...

Buntin, G. D.; Raymer, P. L., 1989: Hessian fly (Diptera: Cecidomyiidae) damage and forage production of winter wheat. Effect of Hessian fly, Mayetiola destructor (Say), damage on the forage production of susceptible and resistant cultivars of soft red winter wheat, Triticum aestivum L., was investigated in three experiments. Hessian fly damage reduced total dry m...

Bickmore, W. A.; Sumner, A. T., 1989: Mammalian chromosome banding - an expression of genome organization. This review covers the techniques of banding, evolutionary and molecular aspects of bands, and the relationship of chromosomal proteins to banding. Advances in molecular biology are beginning to point to features of genome organisation that may pl...

AnjuPappachan; ChinnathambiSubashchandrabose; Satheshkumar,P.S.; Savithri,H.S.; Murthy,M.R.N., 2008: Structure of recombinant capsids formed by the beta -annulus deletion mutant - rCP of Sesbania mosaic virus. A unique feature of several T=3 icosahedral viruses is the presence of a structure called the beta -annulus formed by extensive hydrogen bonding between protein subunits related by icosahedral three-fold axis of symmetry. This unique structure has...

Pagtakhan R.D.; Thomson M.P.; Reis F.J.C.; Reed M.H.; Trevenen C.L.; Berg T.J.; Bensics A.M.; Bigornia L.; Chernick V.; Hershfield E.S., 1982: Tuberculosis and bcg vaccination in pediatric patients the manitoba canada experience. Bulletin of the International Union Against Tuberculosis 57(1): 42

Paul, Jack Leroy, 1965: Solid-phase influence upon yield and phosphorous content of barley. Diss Abstr 25(8): 4340

Sourie, R.; Chaisemartin, C., 1962: Les variations de 1a teneur en calcium total de l'hemolymphe chez Astacus pallipes Lereboullet. Vie et Milieu, 124: 605-613

Arnold, Lloyd E., 1966: Registration of 522 alfalfa. Crop Sci: 610

Dong, Beihua; Silverman, Robert H., 1999: Analysis of RNase L as the prototype of a new family of regulated endoribonucleases. Journal of Interferon & Cytokine Research 19(SUPPL 1): S147, Sept