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Regulation of interstitial cell differentiation in hydra attenuata part 4 nerve cell commitment in head regeneration is position dependent


, : Regulation of interstitial cell differentiation in hydra attenuata part 4 nerve cell commitment in head regeneration is position dependent. Journal of Cell Science 34: 27-38

In hydra, nerve cells are a differentiation product of the interstitial cell, a multipotent stem cell. Nerve cell commitment was examined during head regeneration in H. attenuata. Within 3 h of head removal there was a 10- to 20-fold increase in nerve cell commitment in the tissue which subsequently formed the new head. Nerve cell commitment was unaltered in the remainder of the gastric region. This local increase in nerve cell commitment was responsible for about one half of the new nerve cells formed during head regeneration, while one half differentiated from interstitial cells that migrated into the regenerating tip.

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