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Relationship between maximal oxygen uptake and left ventricular function in exercise

Relationship between maximal oxygen uptake and left ventricular function in exercise

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 44(1): 44-49

Left ventricular systolic time intervals (STI), cardiac output and arterial blood pressures were measured during bicycle ergometer work in 3 groups of 10 young men (aged 20-33 yr) who represented average (.ovrhdot.VO2 max [maximum rate of O2 consumption] = 42-45 ml .cntdot. kg-1 .cntdot. min-1), moderate (.ovrhdot.VO2 max = 50-56 ml .cntdot. kg-1 .cntdot. min-1) and high (.ovrhdot.VO2 max = 59-72 ml .cntdot. kg-1 .cntdot. min-1) levels of cardiovascular fitness. The subjects were studied using noninvasive procedures at steady-state heart rates of approximately 110, 130 and 150 beats .cntdot. min-1. At all exercise levels the fitter subjects displayed slightly shorter values for the preejection period (PEP) compared with less fit groups. Significantly (P < 0.05) larger stroke volumes, longer left ventricular ejection times (LVET), faster mean systolic ejection rates and lower PEP/LVET ratios were found in the group with the highest aerobic capacity compared to the group with the lowest aerobic capacity. Although these observations appear to indicate a superior mean level of left ventricular performance in groups who represent high levels of cardiovascular fitness, the use of STI values by themselves to describe the cardiovascular fitness of an individual apparently is not warranted.

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Accession: 006297591

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PMID: 627498

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