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Relationship between neuron density and oxygen consumption in the guinea pig paramedian cortex during development

, : Relationship between neuron density and oxygen consumption in the guinea pig paramedian cortex during development. Neuroscience Letters 30(2): 109-112

Development-related changes in cortical O2 consumption in the guinea pig were studied with respect to changes in neuronal density. Total O2 consumption was directly related to neuron density, with 5-day-old cortex tissue possessing significantly more neurons per unit area than mature cortical blocks. Mature cortical neurons utilized more O2 than did 5-day-old cortical neurons. Developmental changes in both cortical neuron density and cellular metabolic rates affect O2 consumption patterns in developing guinea pig brain tissue.

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Accession: 006297819

PMID: 7110626

DOI: 10.1016/0304-3940(82)90280-4

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