+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Reproducibility of rest and exercise left ventricular ejection fraction and volumes in chronic aortic regurgitation



Reproducibility of rest and exercise left ventricular ejection fraction and volumes in chronic aortic regurgitation



American Journal of Cardiology 59(15): 1361-1365



To assess the variability of rest and exercise radionuclide ventriculography in patients with aortic regurgitation (AR), 22 patients in stable condition with chronic AR underwent radionuclide ventriculography at rest and during exercise for measurement of left ventricular volumes and ejection fraction (EF) on 2 occasions 3 months apart. For the group, there were no significant differences between the findings of the 2 studies except for a slightly lower exercise end-systolic volume on the second study. The interstudy differences and variabilities (expressed as the standard deviation of differences) for rest and exercise EF and change in EF were 0 .+-. 0.04, +0.02 .+-. 0.05 and +0.01 .+-. 0.05, respectively. Thus, although mean differences were minor, considerable individual variability occurred, the magnitude of which was similar to that reported for other patient populations. In 3 patients who had an initial normal response to exercise (increase in EF .gtoreq. 0.05), the response became abnormal and in 2 who initially had an abnormal response, the response normalized. This variability must be considered in clinical decision-making or in research study design for patients with chronic AR.

(PDF emailed within 0-6 h: $19.90)

Accession: 006315249

Download citation: RISBibTeXText

PMID: 3591692

DOI: 10.1016/0002-9149(87)90920-9


Related references

Alterations in left ventricular volumes and ejection fraction at rest and during exercise in patients with aortic regulation. American Journal of Cardiology 48(1): 17-27, 1981

Comparison of effects of isometric and supine bicycle exercise on left ventricular performance in patients with aortic regurgitation and normal ejection fraction at rest. American Heart Journal 109(6): 1300-1305, 1985

Cine nmr quantification of left and right ventricular volumes ejection fraction and regurgitant fraction in normals and patients with aortic regurgitation. Journal of Nuclear Medicine 29(5 SUPPL): 802, 1988

Course of the radionuclide left ventricular ejection fraction at rest and during exercise in surgically treated asymptomatic chronic aortic insufficiency. Archives des Maladies du Coeur et des Vaisseaux 82(9): 1559-1564, 1989

The relationships between left ventricular volumes and ejection fraction in mitral and aortic regurgitation. Klinische Wochenschrift 53(20): 795-784, 1975

Mechanisms for an abnormal radionuclide left ventricular ejection fraction response to exercise in patients with chronic, severe aortic regurgitation. American Heart Journal 123(2): 453-461, 1992

Exercise testing in asymptomatic or minimally symptomatic aortic regurgitation: relationship of left ventricular ejection fraction to left ventricular filling pressure during exercise. Circulation 67(5): 1091-1100, 1983

Effects of age and sex on left ventricular volumes and ejection fraction at rest and during maximal upright exercise. European Heart Journal 8(ABSTR SUPPL 2): 91, 1987

Course of ejection fraction, regurgitation fraction and ventricular volumes during exertion in chronic aortic insufficiency. Study using technetium 99m gamma-cineangiography. Archives des Maladies du Coeur et des Vaisseaux 78(6): 889-897, 1985

Left ventricular ejection fraction change with exercise versus ejection fraction at rest in coronary artery disease: implications for using ejection fraction variations in making therapeutic decisions. American Journal of Therapeutics 11(3): 164-170, 2004

Chronic aortic regurgitation Natural history of rest and exercise ejection fraction and relation to outcome. Circulation 100(18 SUPPL ): I 519, Nov 2, 1999

Value of rest and exercise changes in left ventricular volumes in the scintigraphic characterization of patients with aortic regurgitation. Circulation Supplement 62(3): III-304, 1980

Left ventricular volume and ejection fraction response to exercise in aortic regurgitation. American Journal of Cardiology 51(8): 1379-1385, 1983

Exercise testing in aortic regurgitation comparison of radio nuclide left ventricular ejection fraction with exercise performance at the anaerobic threshold and peak exercise. American Journal of Cardiology 52(7): 801-808, 1983

Left ventricular shape and mass impact torsional dynamics in asymptomatic patients with chronic aortic regurgitation and normal left ventricular ejection fraction. International Journal of Cardiovascular Imaging 31(7): 1315-1326, 2016