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Reproducibility of ventricular function measurements by contrast angiography

Reproducibility of ventricular function measurements by contrast angiography

Catheterization & Cardiovascular Diagnosis 10(6): 561-572

Interobserver reproducibility of single plane contrast angiographic measurements of end-diastolic volume (EDV/m2), end-systolic volume (ESV/m2), stroke volume (SV/m2) and ejection fraction (EF) was studied in 2 groups of patients. The 1st group (n = 42) was an unselected, consecutive series of patients in which the calculations of volume were performed manually, representing day-to-day results from a clinical quantitative angiographic laboratory. The 2nd group (n = 31) was selected on the basis of optimal filming technique and volume calculations were performed digitally with the aid of a computer. This group characterizes the reproducibility that could be attained for investigational purposes. In the selected group, interobserver reproducibility of 4 regional ejection fractions was determined. The correlation coefficient (r), standard error of the estimate (Sy.x), average difference and 95% confidence limits are given. Measurement variation accounted for 9-15% of the variances in this study for EDV/m2 (consecutive series), indicating that caution is needed when relating contrast angiographic measurements to other (e.g., noninvasive) measures of volume by simple linear regression.

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Accession: 006315313

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PMID: 6509542

DOI: 10.1002/ccd.1810100606

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