+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Risk factors for infection at the operative site after abdominal or vaginal hysterectomy

New England Journal of Medicine 307(27): 1661-1666

Risk factors for infection at the operative site after abdominal or vaginal hysterectomy

We studied risk factors for postoperative infections at the operative site after hysterectomies. Data were collected prospectively on all women undergoing vaginal hysterectomies (323 patients) or abdominal hysterectomies (1125 patients) at the Boston Hospital for Women between February 1976 and April 1978. Logistic-regression analysis indicated that factors significantly associated (P less than 0.05) with a higher risk of infection at the operative site were increased duration of operation, lack of antibiotic prophylaxis, younger age, being a clinic patient, and an abdominal approach. After these variables were accounted for, the variables of obesity, preoperative functional and anatomical diagnoses, postoperative anatomical and pathological diagnoses, estimated blood loss, menopausal status, and operation by a specific surgeon did not add predictive power. An increasing duration of operation was associated with a decreasing effect of antibiotic prophylaxis, the preventive fraction of which diminished from 80 per cent at one hour to an unmeasurable effect at 3.3 hours.

Accession: 006345223

PMID: 6755254

DOI: 10.1056/NEJM198212303072701

Related references

Stozicky V.; Novotna J.; Klabzuba S., 1969: Per operative and post operative complications in abdominal hysterectomy vaginal hysterectomy and in plastic operations on the cervix uteri and the vaginal wall of women. Sbornik Vedeckych Praci Lekarske Fakulty University Karlovy v Hradci Kralove 12(SUPPL 2): 191-204

Young, H.; Bliss, R.; Carey, J.Chris.; Price, C.S., 2012: Beyond core measures: identifying modifiable risk factors for prevention of surgical site infection after elective total abdominal hysterectomy. Despite adherence to the Centers for Medicare and Medicaid Services (CMS) core measures for preventing surgical site infections (SSI), our institution has a >10% rate of SSI after total abdominal hysterectomy (TAH), higher than the 90(th) perce...

Hemsell D.L.; Bernstein S.G.; Bawdon R.E.; Hemsell P.G.; Heard M.C.; Nobles B.J., 1989: Preventing major operative site infection after radical abdominal hysterectomy and pelvic lymphadenectomy. Twenty-one women who underwent radical abdominal hysterectomy and pelvic lymphadenectomy were enrolled in a prospective, comparative, randomized, placebo-controlled clinical trial of antimicrobial prophylaxis. Preoperative endocervical flora was i...

Roovers, J-Paul.W.R.; van der Bom, J.G.; van der Vaart, C.Huub.; Heintz, A.Peter.M., 2003: Hysterectomy and sexual wellbeing: prospective observational study of vaginal hysterectomy, subtotal abdominal hysterectomy, and total abdominal hysterectomy. Objectives: To compare the effects of vaginal hysterectomy, subtotal abdominal hysterectomy, and total abdominal hysterectomy on sexual wellbeing. Design: Prospective observational study over six months. Setting: 13 teaching and non-teaching hospi...

Wang, J-hui.; Zhu, L.; Sun, Z-jing.; Li, L., 2012: Prevention of peri-operative infection with sequential therapy of levofloxacin in patients undergoing laparoscopic hysterectomy, laparoscopic assisted vaginal hysterectomy and transvaginal hysterectomy. To investigate the effect and safety of sequential therapy of levofloxacin in the prevention of peri-operative infections among patients undergoing laparoscopic hysterectomy (LH), laparoscopic assisted vaginal hysterectomy (LAVH) and transvaginal...

Dellinger E.P., 1990: Factors relating to operative care of abdominal injuries predicting infection risk of infection after abdominal injury. Border, J R (Ed ) Blunt Multiple Trauma: Comprehensive Pathophysiology And Care Xxi+861p Marcel Dekker, Inc : New York, New York, Usa; Basel, Switzerland Illus Maps 155-166

Ransom, S.B.; McNeeley, S.G.; White, C.; Diamond, M.P., 1996: A cost analysis of endometrial ablation, abdominal hysterectomy, vaginal hysterectomy, and laparoscopic-assisted vaginal hysterectomy in the treatment of primary menorrhagia. To assess the cost of four procedures performed to treat primary menorrhagia. Retrospective analysis. Setting. A 394-bed womens' teaching hospital. Eighty healthy women undergoing one of the four procedures. Interventions. The study patients...

Jahan, S.; Das, T.R.; Mahmud, N.; Mondol, S.K.; Habib, S.H.; Saha, S.; Yasmin, S.; Joarder, M., 2011: A comparative study among laparoscopically assisted vaginal hysterectomy, vaginal hysterectomy and abdominal hysterectomy: experience in a tertiary care hospital in Bangladesh. The study was undertaken to compare the efficiency and outcome of laparoscopically assisted vaginal hysterectomy (LAVH), total abdominal hysterectomy (TAH) and vaginal hysterectomy (VH) in terms of operative time, cost, estimated blood loss, hospi...

Olsen, M.A.; Higham-Kessler, J.; Yokoe, D.S.; Butler, A.M.; Vostok, J.; Stevenson, K.B.; Khan, Y.; Fraser, V.J., 2010: Developing a risk stratification model for surgical site infection after abdominal hysterectomy. The incidence of surgical site infection (SSI) after hysterectomy ranges widely from 2% to 21%. A specific risk stratification index could help to predict more accurately the risk of incisional SSI following abdominal hysterectomy and would help d...

Tongyoo, A.; Chatthamrak, P.; Sriussadaporn, E.; Limpavitayaporn, P.; Mingmalairak, C., 2015: Risk Assessment of Abdominal Wall Thickness Measured on Pre-Operative Computerized Tomography for Incisional Surgical Site Infection after Abdominal Surgery. The surgical site infection (SSI) is a common complication of abdominal operation. It relates to increased hospital stay, increased healthcare cost, and decreased patient's quality of life. Obesity, usually defined by BMI, is known as one of...