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Risk factors for postoperative pulmonary complication a retrospective multivariate discriminant analysis study



Risk factors for postoperative pulmonary complication a retrospective multivariate discriminant analysis study



Japanese Journal of Anesthesiology 34(7): 978-987



The risk factors which may cause the postoperative pulmonary complication after esophageal cancer surgery were investigated with discriminant analysis. Subjects were 154 patients who received resection and reconstruction of the esophagus at the same time. Variables including clinical findings, laboratory examinations, treatment method and others were selected. Pulmonary complications were defined as at least 1 of the following 6 conditions were satisfied within 2 wk after operation: profuse sputum, PaO2 [arterial O2 pressure] less than 50 mm Hg at room air, massive atelectasis, pneumonia, aspiration pneumonia, and/or interstitial pneumonitis. Postoperative pulmonary complications were found in 40 cases (26.0%). Numbers of risk factors of pulmonary complication before operation, during the operation, and up to 2nd postoperative day were 6, 8 and 11 respectively. Relative importance of risk factors and its change were also displayed. Yielded discriminant scores enables the possibility of postoperative pulmonary complication to be predicted. Age, respiratory maneuvers, stage of cancer, numbers of cigarettes, %VC [vital capacity], preoperative pulse rate, length of operation and timing of extubation were most prominent risk factors among them. Discriminant score gives a tool to improve high risks of postoperative pulmonary complications.

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Accession: 006345278

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PMID: 4057549



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