+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Risk factors in the development of intra ventricular hemorrhage in the preterm neo nate

Archives of Disease in Childhood 57(6): 410-417

Risk factors in the development of intra ventricular hemorrhage in the preterm neo nate

Infants (146) of .ltoreq. 34 wk gestation were repeatedly scanned by real-time ultrasound to diagnose the presence of intraventricular hemorrhage (IVH), its severity, and the timing of onset of the condition. A new method is described for grading the extent of IVH which does not depend on ventricular size. IVH was clearly present in 52 (36%) of the 146 infants and in 32 (50%) of the 64 infants of .ltoreq. 30 wk gestation. Repeated scans accurately timed the onset of IVH in 41 infants, and 32 (78%) had the 1st sign of IVH before 72 h of age. Clinical factors (32) were analyzed for possible correlation with the development of IVH: outborn compared with inborn, administration of sodium bicarbonate, hypothermia, intermittent positive pressure ventilation, continuous positive airways pressure, hypercapnia, severe acidosis and respiratory distress syndrome all reached statistical significance. Analysis of variance showed that respiratory distress syndrome was the most important factor, but severe acidosis had some independent action on the development of IVH. Of 21 infants with hypercapnia (PCO2 [partial pressure of CO2] > 6 kPa [kilopascal]) together with severe acidosis (pH < 7.1), 17 (81%) developed IVH, of which more than half was moderate or severe in degree.

Accession: 006345398

Related references

Satish M.; Kripke S.; Urrutia J.; Katzman G.; Krishnan V.; Amma P.L.S.; Weinfeld I., 1982: Risk factors in the development of intra ventricular hemorrhage in low birth weight neo nates. Pediatric Research 16(4 PART 2): 340A

Lazzara A.; Picard K.; Dykes F.; Ahmann P., 1979: Incidence of intra cerebral hemorrhage in the preterm neo nate importance of optimal stabilization in the immediate post natal period. Clinical Research 27(5): 820A

Cowan, L.D.; Beebe, L.A.; Altshuler, G., 1998: Plackental pathology, maternal hypertension and risk of intra-ventricular hemorrhage in very preterm infants. American Journal of Epidemiology 147(11 SUPPL ): S17, June 1

Williamson W.D.; Desmond M.M.; Wilson G.; Garcia Prats J.; Andrew L., 1980: Early development of preterm neo nates surviving intra ventricular hemorrhage. Pediatric Research 14(4 PART 2): 638

Pomerance J.J.; Richardson C.J., 1973: Hyper pyrexia as a dramatic sign of intra ventricular hemorrhage in the neo nate. Pediatric Research 7(4): 422-194

Levene M.I.; Wigglesworth J.S.; Dubowitz V., 1981: Cerebral structure and intra ventricular hemorrhage in the neo nate a real time ultrasound study. A method for systematic scanning of the neonatal brain with real-time ultrasound is described and the linear array is compared with mechanical sector scanners. Anatomical landmarks recognized on axial, coronal and parasagittal scans are verified b...

Palmer P.; Dubowitz L.M.S.; Levene M.I.; Dubowitz V., 1982: Developmental and neurological progress of preterm infants with intra ventricular hemorrhage and ventricular dilatation. A prospective neurological and developmental assessment was completed at ages 6, 9 and 12 mo. on 39 preterm [human] infants under 34 wk gestation. In the newborn period each infant had an assessment of gestation and sequential neurological and ult...

Hobel C.J.; Hyvarinen M.; Kaplan A.M.; O.W., 1972: Predicting the neo nate and infant at risk by a prospective analysis of pre natal and intra partum high risk factors. Pediatric Research 6(4): 410

Aynsley Green A.; Adrian T.E.; Menchini M.; Bloom S.R., 1982: Development of gut hormone secretion in the preterm neo nate comparison of continuous intra gastric infusions of human milk with intermittent boluses. Regulatory Peptides 3(1): 64

Hawgood S.; Spong J.; Y.V.Y.H., 1982: Germinal matrix and intra ventricular hemorrhage a prospective evaluation of incidence risk factors and evolution in 100 infants less than 1500 grams. Australian Paediatric Journal 18(2): 143