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Risk factors of the cutaneous melanoma phenotype

Risk factors of the cutaneous melanoma phenotype

Archives of Dermatological Research 270(1): 33-36

Of 20 melanoma patients 85% show a prolonged erythema persistence after a marked test erythema of 8 MED [minimal erythematic dose] with 300 nm .+-. 10 nm (control group only 34%). This phenomenon does not correlate with the skin type and is useful in identifying high-risk patients prone to melanoma and light-induced skin cancer (92%). The spontaneous and the UV-C-induced number of sister chromatid exchanges (SCE) per metaphase was significantly higher in peripheral leukocytes of melanoma patients than in normal controls. The attempt was made to establish a risk-spectrum of cutaneous melanoma phenotype.

Accession: 006345447

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PMID: 7259291

DOI: 10.1007/bf00417147

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