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Risk of meningococcal infection for children with different hla phenotypes






Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (1): 54-56

Risk of meningococcal infection for children with different hla phenotypes

A total of 104 children (aged 4 mo. to 13 yr) with meningococcal infection were examined. For control, 600 healthy donors were used. Histocompatibility antigens were determined by the lymphotoxic test. Altogether, 36 antigens of the loci A, B and C were determined. Evidently, the risk of contracting this infection is 6 times greater for persons with HLA-Bw16 phenotype and 3 times greater for persons with HLA-A12 phenotype than for persons with HLA-A1 phenotype.


Accession: 006345634



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