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Role of iron containing blood proteins in intoxication caused by polyamide substances

Role of iron containing blood proteins in intoxication caused by polyamide substances

Voprosy Meditsinskoi Khimii 31(3): 45-48

Chronic treatment (by means of inhalation) of rats with polyamide substances was accompanied by destabilization of erythrocyte membranes causing penetration of hemoglobin into blood serum. Electrophoresis of blood serum proteins in 7.5% polyacrylamide gel exhibited appearance of additional hemoglobin fractions electrophoretic mobility of which corresponded to the 1st and 4th fractions of erythrocyte hemoglobins. Estimation of hemoglobin composition in blood serum might be used for diagnostics of polyamide intoxication.

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Iron-containing blood proteins in poisoning by polyamide compounds. Voprosy Meditsinskoi Khimii 31(3): 45-48, 1985

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