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Role of joint cartilage in the mechanism of development of poly arthritic syndrome in rats induced by mycoplasma fermentans

Zhurnal Eksperimental'noi i Klinicheskoi Meditsiny 22(2): 109-114

Role of joint cartilage in the mechanism of development of poly arthritic syndrome in rats induced by mycoplasma fermentans

In the cartilage of rat joints infected by M. fermentans, dystrophic and immunopathologic changes were observed, resembling the damaged cartilage of patients with rheumatic arthritis in the early period of the disease. In the mechanism of the hyaline cartilage damage, a disturbance in Ca metabolism plays a significant role, connected with the development of light-cellular hyperplasia as well as the persistence at the area of the cartilage of the joints of M. fermentans, the membrane of which has a cytotoxic effect.

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Accession: 006351300

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