Role of serum trans aminases serum glutamic oxal acetic trans aminase and serum glutamic pyruvic trans aminase and alkaline phosphatases in relation to inorganic phosphorus with respect to mercury poisoning in aphanius dispar teleostei of the red sea
Hilmy, A.M.; Shabana, M.B.; Said, M.M.
Comparative Biochemistry and Physiology C Comparative Pharmacology 68(1): 69-74
Decreased serum alkaline phosphatase activity was observed and attributed to slow but constant inhibition of this enzyme by toxicity of Hg2+. Both transaminase enzymes (SGO T [serum glutamic oxalacetic transaminase]) and (SGP T [serum glutamic pyruvic transaminase]) showed higher concentrations in acute and long-term Hg exposure. Prolonged exposure to low concentration of Hg gave a varied effect but showed a downward trend. Although the GO T content of liver tissue was more than GP T, SGP T was a more sensitive reflection to chronic hepatic Hg poisoning, while SGP T was more readily elevated by acute Hg toxicity.