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Serologic survey of neutralizing antibodies against group b coxsackieviruses in a normal population in the delhi area india


Serologic survey of neutralizing antibodies against group b coxsackieviruses in a normal population in the delhi area india



Indian Journal of Medical Research 76(NOV): 656-661



ISSN/ISBN: 0971-5916

Sera from 235 individuals (in the age groups 5-9, 10-14, 15-19, 20-24 and 24 + yr) apparently not suffering from coxsackievirus infection, were for neutralizing antibodies against all the 5 serotypes of group B coxsackievirus by the metabolic inhibition test. The percentage seropositivity in all age groups was 51.6 for B1, 46.38 for B2, 62.55 for B3, 55.32 for B4, 26.81 for B5 and 42.55 for B6. Nearly 90% of the sera had antibodies with a titer of .ltoreq. 1:64 in respect to any of the 6 serotypes. Assuming that the rest (10%) of the sera having antibodies with a titer of > 1:64 represented unrecognized recent infection, it is suggested that a titer of > 1:64 in a single serum sample may indicate a recent infection with the corresponding serotype.

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Accession: 006396815

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