Serum hapto globin and alpha 1 acid glyco protein as indicators of the effectiveness of cis di ammine di chloro platinum in ovarian cancer patients a preliminary report

Fish, R.G.; Gill, T.S.; Adams, M.; Kerby, I.

European Journal of Cancer and Clinical Oncology 20(5): 625-630


ISSN/ISBN: 0277-5379
Accession: 006401521

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Patients (21) with adenocarcinoma of the ovary were given a maximum of 5 courses of CDDP [cis-diamminedichloroplatinum] by i.v. infusion every 4 wk. With 1 exception, the serum levels of haptoglobin and .alpha.1-acid glycoprotein correlate with tumor burden before therapy and at follow-up. A more accurate assessment of the effectiveness of CDDP therapy may be obtained by estimating these serum proteins before each infusion than by an abdominal examination.