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Sexual impotence a double blind study of luteinizing hormone releasing hormone nasal spray vs placebo



Sexual impotence a double blind study of luteinizing hormone releasing hormone nasal spray vs placebo



Neuropsychobiology 1(4): 203-210



A double-blind study comparing application of 1.0 mg LHRH [luteinizing hormone-releasing hormone] nasal spray per day against a placebo was performed in a group of 20 sexually impotent patients in whom no clinical endocrinological pathology was evident. After a 2-wk placebo-spray period, LHRH was given for 4 wk. A 2-wk placebo-spray period followed. A better therapeutic effect was seen in the LHRH as opposed to the placebo group (P = 0.024) 4-6 wk after cessation of LHRH medication. After 4 wk of LHRH medication there were no changes in basal LH/FSH [luteinizing hormone/follicle stimulating hormone] levels or in the LH response after administration of 25 .mu.g LHRH. The FSH response was however significantly lower.

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Accession: 006408678

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