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Somatostatin massive upper gastrointestinal hemorrhage in portal hypertension results of a controlled study



Somatostatin massive upper gastrointestinal hemorrhage in portal hypertension results of a controlled study



Revista Espanola de las Enfermedades del Aparato Digestivo 70(5): 411-414



The authors present an experimental clinical study in which patients with portal hypertension and gastrointestinal hemorrhage were included in a controlled study of two different groups: one submitted to classic treatment with H2 antagonists, Sengstaken tube, blood transfusion and hemodynamic and respiratory control and the other treated with somatostatin and Sengstaken tube. The first group had 16 patients and the second had 19 of similar characteristics. We evaluated control of bleeding, recurrence of hemorrhage, emergency surgery and deferred emergency surgery, and operative and global mortality. From the results of this study it can be deduced that control of hemorrhage with somatostatin was clearly better, 89.4% in comparison with 43.7% for classic treatment, a statistically significant finding. The evaluation of the other parameters was favorable to the individuals in group II although these figures cannot be considered statistically significant.

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