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Specificity of the fluorescent treponemal antibody absorption and treponema pallidum hem agglutination assay tests during pregnancy



Specificity of the fluorescent treponemal antibody absorption and treponema pallidum hem agglutination assay tests during pregnancy



British Journal of Venereal Diseases 54(5): 295-298



In order to determine whether pregancy influences the specificity of the fluorescent treponemal antibody absorption (FTA-ABS) and Treponema pallidum hemagglutination assay (TPHA) tests, these tests and the quantitative fluorescent treponemal antibody (FTA) and Venereal Disease Research Laboratory (VDRL) tests, were carried out simultaneously on 2000 pregnant women who attended for compulsory prenatal screening. In only 1 patient (0.05% of the total investigated) was a positive result to the TPHA test obtained, the specificity of which it was impossible to confirm. The FTA-ABS test gave a weakly reactive result of the borderline type but this was found to be non-specific in only 4 (0.2%) patients. The results of the investigations showed that the specificity of the FRA-ABS and the TPHA tests performed on pregnant women did not differ from the specificity of these tests when carried out on other population groups.

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Accession: 006459057

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