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Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses


Journal of Experimental Medicine 154(2): 541-546
Specificity of the helper T cell for the cytolytic T lymphocyte response to influenza viruses
We have described a model system in which helper T cells are required to mount a primary antiviral cytolytic T lymphocyte response. The radioresistant helper cell can be found in the spleens of mice that have been immunized subcutaneously with influenza viruses 6-8 d previously. These helper cells appear to be type specific but cross-reactive among the subtypes of influenza A viruses. The phenotypes of the interacting cell populations were determined.


Accession: 006459068

PMID: 6973607

DOI: 10.1084/jem.154.2.541



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