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Specificity of the interaction between estrogen and cytoplasmic receptors in cercopithecus griseus uterus and oviduct






Voprosy Meditsinskoi Khimii 28(4): 56-58

Specificity of the interaction between estrogen and cytoplasmic receptors in cercopithecus griseus uterus and oviduct

The specificity of interaction in C. griseus of uterine and oviduct cytosol receptor systems iwth 14 estrogenic substances was characterized. The activity of steroid-receptor interaction was mainly due to the presence of hydroxyl groups in C3- and C17b-positions. The nearest environment of these functional groups in molecules also affected the affinity of steroids to the systems investigated. Analysis of the cytosol estrogen-receptor system specificity from C. griseus, guinea pig, human uterus and oviduct showed the general pattern of the estrogen binding to the above-mentioned systems. Similarity was also noted between these C. griseus and human estrogen-receptor systems.


Accession: 006459089



Related references

Fanchenko, N.D.; Alekseeva, M.L.; Sturchak, S.V.; Novikov, E.A., 1982: Specificity characteristics of estrogen interaction with the cytoplasmic receptors of the uterus and oviducts in green monkeys (Cercopithecus griseus). The specificity of interaction in Cercopithecus griseus uterus and oviduct cytosol receptor systems with 14 estrogenic substances has been characterized. It was shown that the activity of steroid-receptor interaction was mainly due to presence of...

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