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Specificity of the interaction between estrogen and cytoplasmic receptors in cercopithecus griseus uterus and oviduct



Specificity of the interaction between estrogen and cytoplasmic receptors in cercopithecus griseus uterus and oviduct



Voprosy Meditsinskoi Khimii 28(4): 56-58



The specificity of interaction in C. griseus of uterine and oviduct cytosol receptor systems iwth 14 estrogenic substances was characterized. The activity of steroid-receptor interaction was mainly due to the presence of hydroxyl groups in C3- and C17b-positions. The nearest environment of these functional groups in molecules also affected the affinity of steroids to the systems investigated. Analysis of the cytosol estrogen-receptor system specificity from C. griseus, guinea pig, human uterus and oviduct showed the general pattern of the estrogen binding to the above-mentioned systems. Similarity was also noted between these C. griseus and human estrogen-receptor systems.

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Accession: 006459089

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