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Spectinomycin modification 3. spectinomycin analogs with carbon 3' branched chain sugars

, : Spectinomycin modification 3. spectinomycin analogs with carbon 3' branched chain sugars. Journal of Antibiotics (Tokyo) 38(2): 208-219

A variety of C-3'-branched chain analogs of spectinomycin was synthesized via the intermediacy of spectinomycin derived diazoketones. In vitro antibacterial assay of these compounds underscored the importance of H bonding functional groups in this region of the molecule. The most potent of these analogs had activity greater than or equal to the parent.

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