EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Spectral analysis of hippocampal electroencephalography in the freely moving rat effects of centrally active drugs and relations to evoked potentials


Electroencephalography & Clinical Neurophysiology 60(1): 65-77
Spectral analysis of hippocampal electroencephalography in the freely moving rat effects of centrally active drugs and relations to evoked potentials
Hippocampal EEG signals derived from chronically implanted electrodes in the freely moving rat were recorded before and after administration of centrally acting drugs, and analyzed by power and coherence spectra. Eserine, ether or urethane induced a low frequency (3-6 c[cycles]/s) .theta. power and coherence peak in the immobile rat, which was sensitive to atropine or scopolamine. After phencyclidine, .theta. that occurred during walking (7-8 c/s) was virtually abolished by atropine while in the normal rat, absolute .theta. power was not affected by atropine. The residue spectrum, defined as the EEG spectrum with the .theta. harmonics removed, was sensitive to centrally acting drugs. Ether, urethane and pentobarbital suppressed fast waves of 50-100 c/s and under some conditions, enhanced 15-50 c/s waves. Eserine enhanced (30-60 c/s) fast waves during walking while atropine suppressed fast waves and increased irregular slow activity (< 30 c/s). The main effects of drugs and behavior on the residue spectra and on the average evoked potentials following stimulation of the Schaffer collaterals could be explained by a previously proposed model which suggests a continuum of hippocampal activation (tonic input) under the various conditions.


Accession: 006459423



Related references

Spectral analysis of hippocampal EEG in the freely moving rat: effects of centrally active drugs and relations to evoked potentials. Electroencephalography and Clinical Neurophysiology 60(1): 65-77, 1985

Method of recording and quantitative analysis of focal evoked hippocampal potentials in freely moving rats. Zhurnal Vysshei Nervnoi Deiatelnosti Imeni i P Pavlova 29(6): 1315-1318, 1979

Cholinergic gating of hippocampal auditory evoked potentials in freely moving rats. European Neuropsychopharmacology 23(8): 988-997, 2014

Hippocampal field potentials evoked by stimulation of multiple limbic structures in freely moving rats. Neuroscience 4(10): 1467-1478, 1979

Modulation of flash stimulation intensity and frequency: Effects on visual evoked potentials and oscillatory potentials recorded in awake, freely moving mice. Behavioural Brain Research 131(1-2): 105-114, 1st April, 2002

Modulation of flash stimulation intensity and frequency: effects on visual evoked potentials and oscillatory potentials recorded in awake, freely moving mice. Behavioural Brain Research 131(1-2): 105-114, 2002

Correlation between peak times of visually evoked potentials and an amplitude coefficient of acoustically evoked potentials in the superior colliculus on the freely moving rat. Biomedica Biochimica Acta 44(10): 1549-1552, 1985

Effects of morphine and naloxone on hippocampal CA3 field potentials following systemic administration in the freely-moving rat. Brain Research Bulletin 13(2): 241-245, 1984

Effects of beta-casomorphin on dentate hippocampal field potentials in freely moving rats. Biomedica Biochimica Acta 44(5): 749-754, 1985

Effects of a benzodiazepine antagonist, Ro 15-1788, on hippocampal field potentials in freely moving rats. Tohoku Journal of Experimental Medicine 165(4): 261-270, 1991