+ Translate

Spectral analysis of ventilation in elderly subjects awake and asleep

, : Spectral analysis of ventilation in elderly subjects awake and asleep. Journal of Applied Physiology 64(3): 1257-1267

We studied the periodicities of ventilation in elderly subjects using digital comb filtering. Two groups of subjects were studied, those with and without sleep apnea. Measurements were made in wakefulness, stage 1-2 sleep, and where possible in stage 3-4 sleep. For each of the digital filters we calculated the average power of the oscillatory output. To compare subject groups we first specifically determined the average power in the filter with the maximum output. The mean of this measurement was greater in elderly subjects with apnea compared with those without apnea, both during wakefulness and stage 1-2 sleep. In both groups of subjects the cycle time of the major ventilatory oscillations was on the order of 40-60 s. There was no difference in this cycle time between the two groups of subjects in wakefulness or stage 1-2 sleep. Thus, whereas similar oscillatory processes occur in subjects with and without apnea, it is the magnitude of the oscillation that differs between the two groups. These conclusions are supported by analysis of the output of individual filters of the digital comb filter. In both groups, stage 1-2 sleep produces significantly increased oscillations in ventilation. Both in wakefulness and stage 1-2 sleep, significantly greater periodicities occurred in the apneic compared with the nonapneic group. In the few subjects who had sufficient data in stage 3-4 sleep for spectral analysis, ventilatory oscillations were virtually absent in this state. Our data suggest that subjects who develop apnea during sleep have an increased propensity for periodic breathing even while awake.

(PDF 0-2 workdays service)

Accession: 006459473

PMID: 3366740

Submit PDF Full Text: Here

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Parreira, V.F.; Jounieaux, V.; Delguste, P.; Dury, M.; Aubert, G.; Rodenstein, D.O., 1996: Effects of changes in respirator settings on effective ventilation during non-invasive ventilation applied through the nose , in healthy subjects awake and asleep. Journal of Sleep Research 5(SUPPL 1): 167

Pack, A.I.; Millman, R.P., 1986: Changes in control of ventilation, awake and asleep, in the elderly. Journal of the American Geriatrics Society 34(7): 533-544

Parreira, V.; Jounieaux, V.; Aubert, G.; Dury, M.; Lestienne, E.; Delguste, P.; Rodenstein, D.O., 1994: Glottic width responses to nasal intermittent positive pressure ventilation using two-level pressure ventilation in normal subjects awake and asleep. European Respiratory Journal 7(SUPPL 18): 107S

Gonzales, J.; Lombard, F.W.; Borel, C.O., 2005: Pressure support mode improves ventilation in "asleep-awake-asleep" craniotomy. Journal of Neurosurgical Anesthesiology 18(1): 88-88

Parreira, V.F.; Delguste, P.; Jounieaux, V.; Aubert, G.; Dury, M.; Rodenstein, D.O., 1997: Effectiveness of controlled and spontaneous modes in nasal two-level positive pressure ventilation in awake and asleep normal subjects. Study objectives: The purpose of the present study was to compare in awake and asleep healthy subjects, under nasal intermittent positive pressure ventilation (nIPPV) with a two-level intermittent positive pressure device (two-level nIPPV), the ef...

Deras, P.; Moulinié, Gérard.; Maldonado, I.Lima.; Moritz-Gasser, S.; Duffau, H.; Bertram, L., 2013: Intermittent general anesthesia with controlled ventilation for asleep-awake-asleep brain surgery: a prospective series of 140 gliomas in eloquent areas. Awake brain tumor surgery is a unique opportunity for mapping sensorimotor and cognitive functions, allowing the operator to optimize the resection while preserving the patient's quality of life. During this type of procedure, active particip...

Pack A.I.; Silage D.A.; Shore E.T.; Millman R.P.; Fishman A.P., 1985: Spectral analysis of ventilation in elderly subjects. American Review of Respiratory Disease 131(4 SUPPL): A293

Conte, V.; Guzzetti, S.; Porta, A.; Tobaldini, E.; Baratta, P.; Bello, L.; Stocchetti, N., 2009: Spectral analysis of heart rate variability during asleep-awake craniotomy for tumor resection. Anesthesia during asleep-awake craniotomy should provide adequate analgesia and sedation whereas permitting language testing. In this work, we used the analysis of heart rate variability (HRV) to quantify the sympatho-vagal balance and better eval...

Gadhinglajkar, S.; Vitthal, G.Shrinivas.; Sreedhar, R.; Abraham, M., 2008: Anesthesia management of awake craniotomy performed under asleep-awake-asleep technique using laryngeal mask airway: report of two cases. Asleep-awake-asleep technique of anesthesia is used during awake craniotomy with or without securing airway. We assessed this technique using laryngeal mask airway (LMA) in two patients. Patients underwent awake craniotomy for epilepsy surgery and...

Dilmen, O.Korkmaz.; Akcil, E.Fatma.; Oguz, A.; Vehid, H.; Tunali, Y., 2016: Comparison of Conscious Sedation and Asleep-Awake-Asleep Techniques for Awake Craniotomy. NlmCategory="UNASSIGNED">Since awake craniotomy (AC) has become a standard of care for supratentorial tumour resection, especially in the motor and language cortex, determining the most appropriate anaesthetic protocol is very importa...