EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Spectral and kinetic studies on the binding of trithiomolybdate to bovine and canine serum albumin in vitro the interaction with copper


, : Spectral and kinetic studies on the binding of trithiomolybdate to bovine and canine serum albumin in vitro the interaction with copper. Journal of Inorganic Biochemistry 30(4): 261-272

Spectral studies showed that copper and trithiomolybdate participated in a three-way interaction with bovine and canine serum albumin. The interaction with the proteins was affected by increased pH and ionic strength. Kinetic studies of binding equilibria indicated that [35S] trithiomolybdate bound to both albumins at a single site. The affinity of the site, but not the capacity of the protein, was increased by copper. It was concluded that the site was distinct from the N-terminal copper (and nickel) binding site, which is present on BSA but absent from CSA. Whether or not the N-terminal site has a role in copper transport is discussed. Reversible thiomolybdate-copper-protein interactions of this type may play a fundamental role in pathogenesis of Mo-induced syndromes, since as the normal binding patterns are perturbed the interprotein equilibria are altered and the copper distribution patterns are modified.

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006459508

PMID: 3668523

DOI: 10.1016/0162-0134(87)80070-3

PDF Full Text: Spectral and kinetic studies on the binding of trithiomolybdate to bovine and canine serum albumin in vitro the interaction with copper


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Fitch, HS., 1980: Reproductive strategies of reptiles. Contributions to Herpetology, 1: 25-31

Liu, C.; Ma, X.; Li, T.; Zhang, Q., 2016: Kartogenin, transforming growth factor-β1 and bone morphogenetic protein-7 coordinately enhance lubricin accumulation in bone-derived mesenchymal stem cells. Osteoarthritis, a common joint degeneration, can cause breakdown of articular cartilage with the presence of lubricin metabolic abnormalities. Lubricin is a multi-level chondroprotective mucinous glycoprotein in articular joints. Joint defect and...

LUETHY, E., 1962: The hemodynamics of the sufficient and the insufficient right heart. With special reference to thermodilution methods and determination of the end diastolic ventricular volume. Bibliotheca Cardiologica 11: 1-169

Ross, A.; Davis, S., 1990: Point pattern analysis of the spatial proximity of residences prior to diagnosis of persons with Hodgkin's disease. There is some evidence to suggest that the etiology of Hodgkin's disease includes an infectious component. One approach to investigating this possibility is a formal assessment of the geographic and temporal variation in the incidence of the...

Jørgensen, K.A.; Rohr, N.; Elbirk, A.; Svendsen, V.; Birkeland, S.A., 1992: Minnesota-ALG, forced diuresis, careful control of hydration, virus infection prophylaxis and dopamine infusion in human renal transplantation. Transplantation Proceedings 24(1): 358-359

Drouhet, Edouard, 1960: Some mycologie, pathogenetic, and therapeutic aspects of Candida infections. Candida was isolated from 640 of 3000 cultures from patients. 500 of these isolates proved to be C. albicans, and this was considered to be of significance in 350 cases, which were classified as follows: 100 cases of thrush, of which 7 also had Ca...

FARQUHARSON, E., 1955: Operation arnprior, June 20-24, 1955. Canadian Nurse 51(9): 695-697

Wilson P.D.; Nathrath W.B.J.; Trejdosiewicz L.K., 1982: Immuno electron microscopic localization of keratin and luminal epithelial antigens in normal and neoplastic urothelium. Immunoelectron microscope cytochemistry was carried out on 2% paraformaldehyde fixed, 50 .mu. sections of normal urothelium and bladder carcinoma cells in culture using antisera raised in rabbits to human 40-63,000 MW epidermal broad spectrum kera...

Gurevich Rabkina F.P., 1975: Some indices of the functional state of the heart in peptic ulcer patients. Vrachebnoe Delo 1: 22-25

Pang, W.; Sandberg, L.; Laks, P.F.rsman, J., 2007: Corrugated strandboard structural panels. The use of a corrugated shape as a way of improving the strength and stiffness efficiencies of a structural panel has long been used in metal and plastics. This paper presents the design, development and evaluation of a shallow corrugated panel ma...