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Spectral properties of the estrogen induced rat uterus peroxidase ii and some of its derivatives

, : Spectral properties of the estrogen induced rat uterus peroxidase ii and some of its derivatives. Biochemical Journal 201(1): 91-94

The visible absorption spectrum of peroxidase II, isolated from the uterine tissue of estradiol treated rats, and some of its derivatives were recorded. The spectral properties of this enzyme are very similar to eosinophile peroxidase and lactoperoxidase, suggesting that these enzymes may have a similar form of haem as prosthetic group. The uterine peroxidase is modified upon interaction with H2O2 and the difference spectrum of this modified enzyme is similar to that of complex II of lactoperoxidase. The modified enzyme reverted spontaneously to the native enzyme at rates which depended on the concentration of free enzyme and H2O2.

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