+ Translate

Spectral shift of fluorescein and carboxyfluorescein in the anterior chamber of the rabbit eye following systemic administration

, : Spectral shift of fluorescein and carboxyfluorescein in the anterior chamber of the rabbit eye following systemic administration. Current Eye Research 5(5): 337-341

Systemically administered fluorescein is converted to fluorescein glucuronide. The conjugate is fluorescent and interferes with the measurement of fluorescein in the anterior chamber. Carboxyfluorescein is a hydrophilic derivative of fluorescein. In the rabbit, carboxyfluorescein is not converted as readily to a fluorescent metabolite. Thus, carboxyfluorescein has potential advantages as a quantitative fluorophore for studies of aqueous humor dynamics.

(PDF same-day service: $19.90)

Accession: 006459917

PMID: 3720340

DOI: 10.3109/02713688609025171

Submit PDF Full Text: Here

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Kubler, E.; Ruegg, J.C., 1956: Fluorescein diffusion in anterior chamber of rabbit after extirpation of cranial cervical ganglion. Klinische Monatsblatter für Augenheilkunde und für Augenarztliche Fortbildung 128(4): 410-413

Edmond, M.; Yuan, A.; Bell, B.A.; Sharma, A.; DiCicco, R.M.; Tucker, L.; Bena, J.; Tao, Y.K.; Srivastava, S.K., 2016: The Feasibility of Spectral-Domain Optical Coherence Tomography Grading of Anterior Chamber Inflammation in a Rabbit Model of Anterior Uveitis. To determine the feasibility and accuracy of spectral-domain optical coherence tomography (SD-OCT) based grading of anterior chamber cell, using aqueous sampling as a standard, in a rabbit model of anterior uveitis. Adult Dutch-belted rabbits were...

Kleinert, H., 1958: Visible flow of the aqueous humor after partial emptying of the anterior chamber; low-pressure filling of the anterior chamber with fluorescein. Albrecht Von Graefe's Archiv für Ophthalmologie 159(5): 449-458

Sherman, S.H.; Green, K.; Laties, A.M., 1978: The fate of anterior chamber fluorescein in the monkey eye part 1 the anterior chamber outflow pathways. As defined by freeze-dry tissue techniques, there are 2 distinct routes by which fluorescein leaves the anterior chamber of the living rhesus monkey eye. In the 1st or conventional pathway within 5 minutes of the initiation of fluorescein perfusio...

Krause, U.; Eriksen, H.L., 1988: Iris fluorescein angiography and fluorescein gonioscopic photography after implantation of Choyce Mk IX anterior chamber lenses. Patients underwent intracapsular cataract extraction and implantation of a Choyce Mk IX anterior chamber intraocular lens. At fluorescein angiography (FAG) at a mean of 8 months post-operatively, 9 showed leaking from the iridal vessels, and 3 wer...

Banich, A.M.; Bu, P.; Jacob, G.; Fox, L.; Zhang, X.; Perlman, J.I.; Bouchard, C., 2003: Penetration of chlorhexidine into the rabbit anterior chamber following topical administration. Purpose:To evaluate corneal and anterior chamber penetration and corneal toxicity following topical chlorhexidine in a rabbit model Methods: 20% chlorhexidine digluconate stock solution was diluted in saline and 0.5% ethyl alcohol to prepare three...

Gay, S.; Rosso, G., 1964: Influence Of Administration Of Trypsin On The Take And Evolution Of Prostate Autotransplant In The Anterior Chamber Of The Eye Of The Rabbit. Atti Della Accademia Medica Lombarda 19: 223-224

Seto C.; Araie M.; Takase M.; Minoda K., 1984: The effects of fluorescein monoglucuronide on the calculation of the transfer coefficient by diffusion after systemic administration of fluorescein. Flourescein monoglucuronide (FG) from the urine of rabbits, was isolated using modified Chens method. The fluorescent intensity of fluorescein (F) and FG, varying the wavelength of excitation, was determined. To minimize the molar intensity ratio...

Von Goldmann, H., 1950: Fluorescein in the anterior chamber in man. 4 cc. of 10% fluorescein (disodium salt) was injd. intraven. into 10 subjects and the concn. of fluorescein in the anterior chamber, blood plasma and its ultrafiltrate was subsequently detd. The max. concn. of fluorescein in the aqueous humor is 1...

Staiger, Guntram, 1952: Studies on the entrance of fluorescein into the anterior chamber. Exptl. data are given from 127 eyes, which were examined after the method of Amsler and Huber (Ophthalmologica 121 130. 1951). The author has developed a new normal curve for the fluorescein concn. in the anterior chamber after intraven. applicati...